VNP 40101M

Known as: 101M, VNP-40101M, VNP40101M 
A sulfonyl hydrazine prodrug with antineoplastic activity. VNP40101M alkylates the 06 position of guanine, resulting in DNA crosslinking, strand… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2018
024619912018

Papers overview

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2010
2010
PURPOSE An international phase II study of laromustine (VNP40101M), a sulfonylhydrazine alkylating agent, was conducted in… (More)
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2007
2007
PURPOSE Cloretazine (VNP40101M) is a sulfonylhydrazine alkylating agent with significant antileukemia activity. A multicenter… (More)
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2005
2005
The antitumor, DNA-alkylating agent 1,3-bis[2-chloroethyl]-2-nitrosourea (BCNU; Carmustine), which generates 2-chloroethyl… (More)
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2005
2005
Cloretazine {1,2-bis(methylsulfonyl)-1-[(2-chloroethyl)-2-(methylamino)carbonyl]hydrazine; VNP40101M; 101M} is a… (More)
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2005
2005
Cloretazine (VNP40101M; 101M; 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine) is a… (More)
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2004
2004
PURPOSE VNP40101M is a novel sulfonylhydrazine alkylating agent with broad antitumor activity in animal models. As alkylating… (More)
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2003
2003
VNP40101M (1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine) is a sulfonylhydrazine prodrug that… (More)
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2002
2002
Listeriosis is an important food-borne disease that causes high rates of morbidity and mortality. For reasons that are not clear… (More)
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2001
2001
Our laboratory has synthesized and evaluated the anticancer activity of a number of sulfonylhydrazine DNA modifying agents. As a… (More)
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1991
1991
Exudative fluids were collected from packages of five brands of all-beef wieners and inoculated to contain 10(4) to 10(5) CFU of… (More)
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