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VNP 40101M

Known as: 101M, VNP-40101M, VNP40101M 
A sulfonyl hydrazine prodrug with antineoplastic activity. VNP40101M alkylates the 06 position of guanine, resulting in DNA crosslinking, strand… 
National Institutes of Health

Papers overview

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2016
2016
Drug resistance remains an obstacle hindering the success of chemotherapy. Cancer stem cells (CSCs) have been recently found to… 
2014
2014
Histidine-proline-rich glycoprotein (HPRG) is a plasma protein of vertebrates, which has potent antiangiogenic and tumor vessel… 
2012
2012
The development of viral nanoparticles (VNP) displaying multiple copies of the buckyball (C(60)) and their photodynamic activity… 
2004
2004
We report results on the design and implementation of a low cost wireless multi-sensor system to enable the creation of smart… 
2003
2003
PurposeTo investigate the interaction of the electrophilic species generated by the decomposition of the antineoplastic prodrug 1… 
2003
2003
PurposeVNP40101M (1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine) is a sulfonylhydrazine prodrug… 
Highly Cited
2001
Highly Cited
2001
Our laboratory has synthesized and evaluated the anticancer activity of a number of sulfonylhydrazine DNA modifying agents. As a… 
1977
1977