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VNP 40101M

Known as: 101M, VNP-40101M, VNP40101M 
A sulfonyl hydrazine prodrug with antineoplastic activity. VNP40101M alkylates the 06 position of guanine, resulting in DNA crosslinking, strand… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Alkylating Agentslaromustine

Narrower (1)

Cloretazine
hydroxyurea/VNP40101Mtemozolomide/VNP40101M

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently
Drug resistance remains an obstacle hindering the success of chemotherapy. Cancer stem cells (CSCs) have been recently found to… 
2012
2012
Photodynamic activity of viral nanoparticles conjugated with C60.
The development of viral nanoparticles (VNP) displaying multiple copies of the buckyball (C(60)) and their photodynamic activity… 
2011
2011
Landslide hazard zonation around Gilgel Gibe-II Hydroelectric project, Southwestern Ethiopia
The present study was carried out along the newly constructed road from Fofa town to Gilgel Gibe-II powerhouse in South western… 
2010
2010
Earthworm and Soil Carbon Sequestration after Twenty One Years of Continuous No-tillage Corn-Legume Rotation in Indonesia
Soil carbon and earthworm are important components in sustainable tropical agro-ecosystem. Longterm experiment was initially… 
2010
2010
Perancangan Alat Pemantau Keberadaan Anak secara Nirkabel
In this project a wireless device was designed, based on 2.4 GHz transceivers for children surveillance, in public places. The… 
2007
2007
Geophysical exploration of Antarctic blue ice areas (BIAs) for paleoclimate applications : a doctoral thesis by
Antarctic blue ice areas (BIAs) cover about 1 % of Antarctic surface area. The BIAs are known to have very old ice at the surface… 
2004
2004
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): I. Direct inhibition of O6-alkylguanine-DNA alkyltransferase (AGT) by electrophilic species generated by…
PurposeTo investigate the interaction of the electrophilic species generated by the decomposition of the antineoplastic prodrug 1… 
2004
2004
Smart Brick-A Low Cost , Modular Wireless Sensor For Civil Structure Monitoring
We report results on the design and implementation of a low cost wireless multi-sensor system to enable the creation of smart… 
Highly Cited
2001
Highly Cited
2001
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino)carbonylhydrazine (101M): a novel sulfonylhydrazine prodrug with broad-spectrum antineoplastic activity.
Our laboratory has synthesized and evaluated the anticancer activity of a number of sulfonylhydrazine DNA modifying agents. As a… 
Review
1992
Review
1992
The Advising Connection: A Training Program for Faculty Advisors.
At Amarillo College (AC) in Texas, academic advising is provided by certified counselors at the Advising and Counseling center in… 
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