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laromustine

A sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (3)

CloretazineOnriginVNP 40101M

Broader (2)

HydrazinesSulfonamides
NCIt Antineoplastic Agent Terminology

Papers overview

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2016
2016
Title Page Biotransformation and Rearrangement of Laromustine
2014
2014
Optimization of a Chemical Genetic Screen for Sensitization to Laromustine
2013
2013
(VNP40101M) in patients with acute myeloid leukemia in first relapse high-dose continuous infusion cytarabine alone or with laromustine Phase 3 randomized, placebo-controlled, double-blind study of
2010
2010
Gateways to clinical trials.
[¹¹C]RAC; (18)F-Fluoromisonidazole; 89-12; 9-[¹⁸F]Fluoropropyl-(+)-dihydrotetrabenazine; Adalimumab, Adecatumumab, ADMVA, ADXS-11… 
Review
2009
Review
2009
FDA Pipeline preview, October 2009 (doxorubicin, trabectedin, carisbamate, alogliptin/pioglitazone, HPV vaccine, pralatrexate, romidepsin, hyaluronic acid, laromustine, clofarabine, prGCD, KNS-760704…
Recent FDA action (through October 2009) related to doxorubicin, trabectedin, carisbamate, alogliptin/pioglitazone, HPV vaccine… 
2009
2009
Gateways to clinical trials.
(+)-Dapoxetine hydrochloride, [(123)I]-BZA, 9-Aminocamptothecin; Abacavir sulfate/lamivudine, Adalimumab, Adefovir dipivoxil… 
2009
2009
Gateways to clinical trials.
(-)-Gossypol; Abacavir sulfate/lamivudine, ACAM-1000, ACE-011, Agomelatine, AGS-004, Alemtuzumab, Alvocidib hydrochloride, AMG…