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Ursodiol

Known as: Acid, Ursodeoxycholic, 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid, (3?,5?,7?)-3,7-dihydroxycholan-24-oic acid 
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese… 
National Institutes of Health

Related topics

Related topics

42 relations

Narrower (25)

23-methylursodeoxycholic acid24-norursodeoxycholic acid3,6-dihydroxy-6-methylcholanoic acid6-fluoro-ursodeoxycholic acid
Bile Acids and SaltsBiliary cirrhosisCholelithiasisDrug Allergy

Broader (2)

Cholagogues and CholereticsUrsodeoxycholate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Ursodeoxycholic Acid Modulates E2F-1 and p53 Expression through a Caspase-independent Mechanism in Transforming Growth Factor β1-induced Apoptosis of Rat Hepatocytes*
Transforming growth factor β1 (TGF-β1)-induced hepatocyte apoptosis is associated with activation of E2F transcription factors… 
Review
2000
Review
2000
Drug-induced liver disease.
This year's review has been divided into five sections: The first describes the natural history of drug-induced liver disease… 
Highly Cited
1995
Highly Cited
1995
Effect of tauroursodeoxycholic and ursodeoxycholic acid on ethanol-induced cell injuries in the human Hep G2 cell line.
Highly Cited
1994
Highly Cited
1994
Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis?
Review
1994
Review
1994
Strategy and planning for chemopreventive drug development: Clinical development plans
At the National Cancer Institute, Division of Cancer Prevention and Control, the Chemoprevention Branch and Agent Development… 
Review
1987
Review
1987
Ursodeoxycholic Acid for Primary Biliary Cirrhosis?
BACKGROUND Primary biliary cirrhosis is a rare autoimmune liver disease and an effective treatment has been difficult to… 
Highly Cited
1984
Highly Cited
1984
Effect of Ursodeoxycholic Acid on Biliary Bile Acid and Bile Lipid Composition in Gallstone Patients
In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250, 500, 750, 1,000, and 1… 
Highly Cited
1982
Highly Cited
1982
Bioluminescence measurement of primary bile acids using immobilized 7 alpha-hydroxysteroid dehydrogenase: application to serum bile acids.
A simple, rapid, and sensitive bioluminescence method for measuring primary bile acids has been developed and validated. The… 
Highly Cited
1980
Highly Cited
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… 
Highly Cited
1979
Highly Cited
1979
Cholesterol gallstone formation and prevention by chenodeoxycholic and ursodeoxycholic acids. A new hamster model.
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