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Ursodiol
Known as:
Acid, Ursodeoxycholic
, 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid
, (3?,5?,7?)-3,7-dihydroxycholan-24-oic acid
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A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese…
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National Institutes of Health
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Related topics
Related topics
42 relations
Narrower (25)
23-methylursodeoxycholic acid
24-norursodeoxycholic acid
3,6-dihydroxy-6-methylcholanoic acid
6-fluoro-ursodeoxycholic acid
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Bile Acids and Salts
Biliary cirrhosis
Cholelithiasis
Drug Allergy
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Broader (2)
Cholagogues and Choleretics
Ursodeoxycholate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Ursodeoxycholic Acid Modulates E2F-1 and p53 Expression through a Caspase-independent Mechanism in Transforming Growth Factor β1-induced Apoptosis of Rat Hepatocytes*
S. Solá
,
Xiaomin Ma
,
R. Castro
,
B. Kren
,
C. Steer
,
C. Rodrigues
Journal of Biological Chemistry
2003
Corpus ID: 19710335
Transforming growth factor β1 (TGF-β1)-induced hepatocyte apoptosis is associated with activation of E2F transcription factors…
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Review
2000
Review
2000
Drug-induced liver disease.
W. Mayoral
,
J. Lewis
Current Opinion in Gastroenterology
2000
Corpus ID: 23025523
This year's review has been divided into five sections: The first describes the natural history of drug-induced liver disease…
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Highly Cited
1995
Highly Cited
1995
Effect of tauroursodeoxycholic and ursodeoxycholic acid on ethanol-induced cell injuries in the human Hep G2 cell line.
Manuela G. Neuman
,
Ross G. Cameron
,
Neil H. Shear
,
S. Bellentani
,
C. Tiribelli
Gastroenterology
1995
Corpus ID: 25310270
Highly Cited
1994
Highly Cited
1994
Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis?
L. Colombato
,
F. Alvarez
,
Jean Côté
,
P. Huet
Gastroenterology
1994
Corpus ID: 25972420
Review
1994
Review
1994
Strategy and planning for chemopreventive drug development: Clinical development plans
MD Gary J. Kelloff
,
PhD James A. Crowell
,
+13 authors
PhD5 Caroline C. Sigman
1994
Corpus ID: 28557431
At the National Cancer Institute, Division of Cancer Prevention and Control, the Chemoprevention Branch and Agent Development…
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Review
1987
Review
1987
Ursodeoxycholic Acid for Primary Biliary Cirrhosis?
C. Gluud
,
E. Christensen
Cochrane Database of Systematic Reviews
1987
Corpus ID: 28720169
BACKGROUND Primary biliary cirrhosis is a rare autoimmune liver disease and an effective treatment has been difficult to…
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Highly Cited
1984
Highly Cited
1984
Effect of Ursodeoxycholic Acid on Biliary Bile Acid and Bile Lipid Composition in Gallstone Patients
A. Stiehl
,
R. Raedsch
,
G. Rudolph
,
S. Walker
Hepatology
1984
Corpus ID: 20590428
In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250, 500, 750, 1,000, and 1…
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Highly Cited
1982
Highly Cited
1982
Bioluminescence measurement of primary bile acids using immobilized 7 alpha-hydroxysteroid dehydrogenase: application to serum bile acids.
A. Roda
,
L. Kricka
,
M. Deluca
,
A. Hofmann
Journal of Lipid Research
1982
Corpus ID: 12730467
A simple, rapid, and sensitive bioluminescence method for measuring primary bile acids has been developed and validated. The…
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Highly Cited
1980
Highly Cited
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
H. Fromm
,
G. Carlson
,
A. Hofmann
,
S. Farivar
,
P. Amin
American Journal of Physiology
1980
Corpus ID: 22972148
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver…
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Highly Cited
1979
Highly Cited
1979
Cholesterol gallstone formation and prevention by chenodeoxycholic and ursodeoxycholic acids. A new hamster model.
B. Pearlman
,
G. Bonorris
,
+4 authors
L. Schoenfield
Gastroenterology
1979
Corpus ID: 10824884
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