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Ursodiol

Known as: Acid, Ursodeoxycholic, 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid, (3?,5?,7?)-3,7-dihydroxycholan-24-oic acid 
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese… 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Endoplasmic reticulum (ER) stress is a key link between obesity, insulin resistance, and type 2 diabetes. Here, we provide… 
Review
2004
Review
2004
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease, characterized by fibrosing inflammation and… 
Review
2004
Review
2004
No effective medical therapy is available for all patients with nonalcoholic steatohepatitis (NASH). Ursodeoxycholic acid (UDCA… 
Review
2002
Review
2002
Ursodeoxycholic acid (UCDA) is increasingly used for the treatment of cholestatic liver diseases. Experimental evidence suggests… 
Highly Cited
2001
Highly Cited
2001
Patients with ulcerative colitis have an increased risk for colorectal neoplasia; this risk approaches 0.5% to 1% per year of… 
Highly Cited
2000
Highly Cited
2000
  • P. Rosenthal
  • IDrugs : the investigational drugs journal
  • 2000
  • Corpus ID: 30831878
The latest advances in hepatology were presented in oral and poster presentations. In order to cover the varying subspecialties… 
Review
1999
Review
1999
  • A. Hofmann
  • Archives of internal medicine
  • 1999
  • Corpus ID: 21211064
Bile acids, the water-soluble, amphipathic end products of cholesterol metabolism, are involved in liver, biliary, and intestinal… 
Highly Cited
1997
Highly Cited
1997
Background There is no satisfactory medical therapy for patients with primary sclerosing cholangitis. Ursodiol (ursodeoxycholic… 
Highly Cited
1994
Highly Cited
1994
BACKGROUND Ursodiol (ursodeoxycholic acid) therapy leads to major improvements in patients with primary biliary cirrhosis. The… 
Highly Cited
1991
Highly Cited
1991
BACKGROUND In primary biliary cirrhosis the hepatic lesions may result, at least in part, from the intracellular accumulation of…