Ursodeoxycholate

 
National Institutes of Health

Papers overview

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2010
2010
Clinical observations suggest that ursodeoxycholate (UDCA) may protect from hepatocellular carcinoma in cirrhotic patients… (More)
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2004
2004
BACKGROUND & AIMS Preclinical studies in animal models, human epidemiological data, and clinical trials in patients with… (More)
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2003
2003
Ethinylestradiol (EE) administration (5 mg/kg, s.c., daily for 5 days) to rats leads to cholestasis, and its derivative EE 17beta… (More)
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Highly Cited
1999
Highly Cited
1999
Human dihydrodiol dehydrogenase (DD) isoforms are aldo-keto reductases (AKRs) that activate polycyclic aromatic hydrocarbons… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS The mouse mdr2 gene encodes a P-glycoprotein expressed in the hepatocanalicular membrane. Inactivation of this… (More)
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Highly Cited
1995
Highly Cited
1995
Ursodeoxycholate (UDCA), a hydrophilic bile salt, ameliorates hepatocellular injury by toxic bile salts and is used to treat… (More)
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1995
1995
BACKGROUND & AIMS To explain the greater hepatoprotective effect of tauroursodeoxycholic acid vs. ursodeoxycholic acid, the… (More)
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1994
1994
BACKGROUND/AIMS Ursodeoxycholic acid attenuates hepatocellular injury in cholestatic disorders, possibly by counteracting… (More)
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1991
1991
The protective effect of ursodeoxycholate conjugates against bile salt hepatotoxicity was studied in chronic bile fistula rats… (More)
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1986
1986
To define whether side-chain length influences the physiologic properties of bile acids, nor-ursodeoxycholate (nor-UDC), the C23… (More)
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