24-norursodeoxycholic acid

BACKGROUND & AIM Primary sclerosing cholangitis (PSC) represents a devastating bile duct disease, currently lacking effective… (More)

 

Primary sclerosing cholangitis (PSC) represents a fibro-obliterative bile duct disease with unpredictable individual clinical… (More)

Chronic inflammatory bile duct diseases such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) result… (More)

BACKGROUND Primary sclerosing cholangitis (PSC) remains a challenging disease to manage. The main goals are prevention of disease… (More)

UNLABELLED NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic… (More)

UNLABELLED 24-norursodeoxycholic acid (norUDCA), a side chain-modified ursodeoxycholic acid derivative, has dramatic therapeutic… (More)

Patients with chronic cholestatic diseases of the biliary tree, such as primary sclerosing cholangitis (PSC), have long suffered… (More)

BACKGROUND & AIMS Current therapy for primary sclerosing cholangitis is of limited efficacy. Multidrug resistance gene 2 knockout… (More)

In this study, we compared in vitro calcium binding by the taurine and glycine conjugates of the major bile acids in human bile… (More)