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Urokinase Plasminogen Activator Receptor
Known as:
U PA Receptor
, Urokinase Plasminogen Activator Surface Receptor
, CD87
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An extracellular receptor specific for UROKINASE-TYPE PLASMINOGEN ACTIVATOR. It is attached to the cell membrane via a GLYCOSYLPHOSPHATIDYLINOSITOL…
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National Institutes of Health
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Related topics
Related topics
20 relations
CD80 Antigens
CD86 Antigen
Chemotaxis
Clusters of differentiation
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Broader (1)
Membrane Glycoproteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
The urokinase receptor as a potential target in cancer therapy.
J. Rømer
,
B. Nielsen
,
M. Ploug
Current pharmaceutical design
2004
Corpus ID: 35810010
The glycolipid-anchored receptor for urokinase-type plasminogen activator (uPAR) is essential for cell-surface associated…
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Highly Cited
2002
Highly Cited
2002
Regulation of DNA Methylation in Human Breast Cancer
Yongjing Guo
,
Pouya Pakneshan
,
Julienne Gladu
,
A. Slack
,
M. Szyf
,
S. Rabbani
Journal of Biological Chemistry
2002
Corpus ID: 6343402
Urokinase-type plasminogen activator (uPA) is a member of the serine protease family and can break down various components of the…
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Highly Cited
1999
Highly Cited
1999
Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction.
M. Yebra
,
L. Goretzki
,
M. Pfeifer
,
B. M. Mueller
Experimental Cell Research
1999
Corpus ID: 22415871
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) participate in matrix degradation and cell migration by…
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Highly Cited
1997
Highly Cited
1997
The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction
G. Høyer-Hansen
,
N. Behrendt
,
M. Ploug
,
K. Danø
,
K. Preissner
FEBS Letters
1997
Corpus ID: 22465256
Highly Cited
1996
Highly Cited
1996
Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization.
A. Kindzelskii
,
Z. Laska
,
R. Todd
,
H. Petty
Journal of Immunology
1996
Corpus ID: 40015187
Previous studies have shown that the leukocyte integrin CR3 (CD11b/CD18) is physically associated with the urokinase-type…
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Highly Cited
1996
Highly Cited
1996
Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion.
S. S. Okada
,
Stephen R. Grobmyer
,
Elliot S. Barnathan
Arteriosclerosis, Thrombosis and Vascular Biology
1996
Corpus ID: 21283735
Smooth muscle cell (SMC) migration is an early response to vascular injury and contributes to the development of intimal…
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Highly Cited
1996
Highly Cited
1996
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration.
M. Yebra
,
G. Parry
,
+4 authors
D. Cheresh
Journal of Biological Chemistry
1996
Corpus ID: 5894362
The urokinase plasminogen activator (uPA) interacts with its cell surface receptor (uPAR), providing an inducible, localized cell…
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Highly Cited
1995
Highly Cited
1995
Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo.
Ikuko F. Mizukami
,
N. Faulkner
,
M. Gyetko
,
R. G. Sitrin
,
Robert F. Todd
Blood
1995
Corpus ID: 39445741
The receptor for urokinase plasminogen activator (uPA-R, CD87) is a glycosylphosphatidylinositol (GPI)-anchored 50 to 65 kD…
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Highly Cited
1995
Highly Cited
1995
Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma.
C. Gladson
,
V. Pijuan-Thompson
,
M. Olman
,
G. Gillespie
,
I. Z. Yacoub
American Journal of Pathology
1995
Corpus ID: 44494726
To understand the role of urokinase (u-PA) and the urokinase receptor (u-PAR) in malignant astrocytoma cell invasion of normal…
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Review
1994
Review
1994
Receptor‐mediated endocytosis of plasminogen activators and activator/inhibitor complexes
P. Andreasen
,
L. Sottrup-jensen
,
+4 authors
J. Gliemann
FEBS Letters
1994
Corpus ID: 23198349
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