Urokinase Plasminogen Activator Receptor

Known as: U PA Receptor, Urokinase Plasminogen Activator Surface Receptor, CD87 
An extracellular receptor specific for UROKINASE-TYPE PLASMINOGEN ACTIVATOR. It is attached to the cell membrane via a GLYCOSYLPHOSPHATIDYLINOSITOL… (More)
National Institutes of Health

Related topics

Related topics

20 relations
CD80 AntigensCD86 AntigenChemotaxisClusters of differentiation
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Broader (1)

Membrane Glycoproteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) is a cause of proteinuric kidney disease, compromising both native and transplanted… (More)
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Highly Cited
2011
Highly Cited
2011
Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients
INTRODUCTION suPAR is the soluble form of the urokinase plasminogen activator receptor (uPAR), which is expressed in various… (More)
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Highly Cited
2010
Highly Cited
2010
Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population.
BACKGROUND Low-grade inflammation is thought to contribute to the development of cardiovascular disease (CVD), type-2 diabetes… (More)
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Highly Cited
2008
Highly Cited
2008
Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors.
Human neural and mesenchymal stem cells have been identified for cell-based therapies in regenerative medicine and as vehicles… (More)
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Highly Cited
2008
Highly Cited
2008
Modification of kidney barrier function by the urokinase receptor
Podocyte dysfunction, represented by foot process effacement and proteinuria, is often the starting point for progressive kidney… (More)
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Highly Cited
1999
Highly Cited
1999
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
Cardiac rupture is a fatal complication of acute myocardial infarction lacking treatment. Here, acute myocardial infarction… (More)
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Highly Cited
1995
Highly Cited
1995
Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer.
Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action… (More)
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Highly Cited
1995
Highly Cited
1995
Urokinase plasminogen activator receptor, beta 2-integrins, and Src- kinases within a single receptor complex of human monocytes
The glycosylphosphatidylinositol (GPI)-anchored membrane protein urokinase plasminogen activator-receptor (uPA-R; CD87) is one of… (More)
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Highly Cited
1994
Highly Cited
1994
Identification of the urokinase receptor as an adhesion receptor for vitronectin.
Urokinase receptors, expressed on surfaces of many cell types, focus to the pericellular space plasminogen-dependent proteolysis… (More)
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Highly Cited
1991
Highly Cited
1991
Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol.
The cellular receptor for human urokinase-type plasminogen activator (u-PAR) is shown by several independent criteria to be a… (More)
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