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Urokinase Plasminogen Activator Receptor

Known as: U PA Receptor, Urokinase Plasminogen Activator Surface Receptor, CD87 
An extracellular receptor specific for UROKINASE-TYPE PLASMINOGEN ACTIVATOR. It is attached to the cell membrane via a GLYCOSYLPHOSPHATIDYLINOSITOL… 
National Institutes of Health

Related topics

Related topics

20 relations
CD80 AntigensCD86 AntigenChemotaxisClusters of differentiation

Broader (1)

Membrane Glycoproteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
The urokinase receptor as a potential target in cancer therapy.
The glycolipid-anchored receptor for urokinase-type plasminogen activator (uPAR) is essential for cell-surface associated… 
Highly Cited
2002
Highly Cited
2002
Regulation of DNA Methylation in Human Breast Cancer
Urokinase-type plasminogen activator (uPA) is a member of the serine protease family and can break down various components of the… 
Highly Cited
1999
Highly Cited
1999
Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction.
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) participate in matrix degradation and cell migration by… 
Highly Cited
1998
Highly Cited
1998
Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer.
Overexpression of tissue factor (TF) is characteristically observed in advanced pancreatic cancer and has been associated with… 
Highly Cited
1997
Highly Cited
1997
The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction
Highly Cited
1996
Highly Cited
1996
Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization.
Previous studies have shown that the leukocyte integrin CR3 (CD11b/CD18) is physically associated with the urokinase-type… 
Highly Cited
1996
Highly Cited
1996
Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion.
Smooth muscle cell (SMC) migration is an early response to vascular injury and contributes to the development of intimal… 
Highly Cited
1996
Highly Cited
1996
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration.
The urokinase plasminogen activator (uPA) interacts with its cell surface receptor (uPAR), providing an inducible, localized cell… 
Highly Cited
1995
Highly Cited
1995
Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo.
The receptor for urokinase plasminogen activator (uPA-R, CD87) is a glycosylphosphatidylinositol (GPI)-anchored 50 to 65 kD… 
Review
1994
Review
1994
Receptor‐mediated endocytosis of plasminogen activators and activator/inhibitor complexes
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