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Uric Acid

Known as: 7,9-Dihydro-1H-purine-2,6,8(3H)-trione, Acid, Uric, Trioxopurine 
A waste product left over from normal chemical processes in the body and found in the urine and blood. Abnormal buildup of uric acid in the body may… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (17)

1,3,7,9-tetramethyluric acid1,3,7-trimethyluric acid1,3-dimethyluric acid1,7-dimethyl-8-oxoenprofylline
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Broader (4)

AcidsAntioxidantsFlavinsoxypurine
Chronic Urate NephropathyGoutIn BloodSerum urate measurement
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Uric acid and cardiovascular risk.
This review summarizes relevant studies concerning uric acid and possible links to hypertension, renal disease, and… 
Highly Cited
2006
Highly Cited
2006
Gout-associated uric acid crystals activate the NALP3 inflammasome
Development of the acute and chronic inflammatory responses known as gout and pseudogout are associated with the deposition of… 
Highly Cited
2006
Highly Cited
2006
A causal role for uric acid in fructose-induced metabolic syndrome.
The worldwide epidemic of metabolic syndrome correlates with an elevation in serum uric acid as well as a marked increase in… 
Review
2003
Review
2003
Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?
Hyperuricemia is associated with hypertension, vascular disease, renal disease, and cardiovascular events. In this report, we… 
Highly Cited
2001
Highly Cited
2001
Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism
An elevation in circulating serum uric acid is strongly associated with the development of hypertension and renal disease, but… 
Review
2000
Review
2000
Serum Uric Acid and Cardiovascular Mortality: The NHANES I Epidemiologic Follow-up Study, 1971-1992
ContextAlthough many epidemiological studies have suggested that increased serum uric acid levels are a risk factor for… 
Review
1999
Review
1999
Serum Uric Acid and Risk for Cardiovascular Disease and Death: The Framingham Heart Study
The association of serum uric acid with cardiovascular disease has been appreciated for nearly half a century (1). Several… 
Highly Cited
1996
Highly Cited
1996
The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay.
A simple, automated test measuring the ferric reducing ability of plasma, the FRAP assay, is presented as a novel method for… 
Highly Cited
1991
Highly Cited
1991
Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration.
OBJECTIVE To define the relationship, if any, between insulin-mediated glucose disposal and serum uric acid. DESIGN Cross… 
Highly Cited
1981
Highly Cited
1981
Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.
During primate evolution, a major factor in lengthening life-span and decreasing age-specific cancer rates may have been improved… 
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