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1,3-dimethyluric acid

 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Pharmacokinetic parameters of theophylline and one of its metabolites, 1,3-dimethyluric acid (1,3-DMU), were compared after… Expand
Highly Cited
2005
Highly Cited
2005
Organic anion transporter 2 (Oat2 [SLC22A7]) is a multispecific organic anion transporter. Although several substrates of human… Expand
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Highly Cited
1995
Highly Cited
1995
1. Fluvoxamine and seven other selective serotonin reuptake inhibitors (SRRI) were tested for their ability to inhibit a number… Expand
Highly Cited
1995
Highly Cited
1995
Studies were undertaken to determine which human P450 enzymes catalyze the metabolism of theophylline to 1,3-dimethyluric acid (1… Expand
Highly Cited
1995
Highly Cited
1995
1. Theophylline metabolism was studied using seven human cytochrome P-450 isoforms (CYPs), namely CYP1A1, 1A2, 2A6, 2B6, 2D6, 2E1… Expand
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Highly Cited
1987
Highly Cited
1987
1. A radiometric high performance liquid chromatographic method is described for the assay of theophylline metabolism in vitro by… Expand
1984
1984
Summary: Eleven healthy volunteers were given maintenance treatment with oral theophylline in increasing doses (210–1,260 mg/day… Expand
Highly Cited
1982
Highly Cited
1982
Theophylline (1,3-dimethylxanthine) is a constituent of numerous bronchodilator preparations and is widely used in the treatment… Expand
Highly Cited
1982
Highly Cited
1982
Elimination kinetics of theophylline and its major metabolites were investigated in 14 healthy adults in single‐dose studies and… Expand
Highly Cited
1952
Highly Cited
1952
The intermediary metabolism of theophylline has been the subject of a number of studies, but its fate in the body is still… Expand
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