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USF1 gene

Known as: bHLHb11, Upstream Transcription Factor 1 Gene, USF1 
This gene plays a role in the transcriptional activation of genes involved in glucose and lipid homeostasis.
National Institutes of Health

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Homo sapiensHyperlipidemiaTranscriptional ActivationTranscriptional Regulation

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USF1 wt Allele

Papers overview

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2008
2008
Association Analysis of Allelic Variants of USF1 in Coronary Atherosclerosis
Objective—USF1 regulates the transcription of more than 40 cardiovascular related genes and is well established as a gene… 
2007
2007
Associations between USF1 gene variants and cardiovascular risk factors in the Quebec Family Study
Cardiovascular (CVD) risk factors are under the influence of environmental and genetic factors. Human upstream transcription… 
2006
2006
Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene–gene interactions
Upstream transcription factor 1 (USF1) regulates the expression of many genes involved in lipid and glucose metabolism, among… 
2003
2003
Cloning and characterization of a novel splicing isoform of USF1.
The ubiquitous basic helix-loop-helix transcription factor USFs encoded by two distinct genes (USF1 and USF2) recognize a core… 
1996
1996
Functional characterization of COM, a DNA region required for cooperation between AP-1 sites in urokinase gene transcription.
The inducible uPA enhancer contains two phorbol ester responsive elements: the combined PEA3/AP-1A and a downstream AP-1B site… 
1995
1995
DNase I hypersensitivity sites and nuclear protein binding on the fatty acid synthase gene: identification of an element with properties similar to known glucose-responsive elements.
We have shown previously that fatty acid synthase (FAS) gene expression is positively regulated by glucose in rat adipose tissue… 
Highly Cited
1991
Highly Cited
1991
The bidirectional promoter of the divergently transcribed mouse Surf-1 and Surf-2 genes.
The ubiquitously expressed mouse Surf-1 and Surf-2 genes are divergently transcribed, and their heterogeneous start sites are… 
1990
1990
The human cytomegalovirus 2.7-kilobase RNA promoter contains a functional binding site for the adenovirus major late transcription factor
We have examined the factors which influence the expression of a major 2.7-kilobase (kb) early transcript encoded by the long… 
1989
1989
Analysis by cell-free transcription of the liver-specific pyruvate kinase gene promoter
A DNA fragment spanning nucleotides -183 to -4 with respect to the cap site of the rat L-type pyruvate kinase (L-PK) gene… 
Highly Cited
1987
Highly Cited
1987
The major late transcription factor binds to and activates the mouse metallothionein I promoter.
Human (HeLa) cells contain a protein, MLTF, which specifically binds to a DNA sequence in the adenovirus 2 major late promoter… 
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