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UK 453,061

Known as: UK453061, UK 453061, UK-453061 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

NitrilesPyrazoles

Narrower (1)

lersivirine

Papers overview

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2012
2012
Efficacy and safety of lersivirine (UK-453,061) versus efavirenz in antiretroviral treatment-naive HIV-1-infected patients: week 48 primary analysis results from an ongoing, multicenter, randomized…
OBJECTIVE A 96-week clinical study was planned to estimate the antiviral activity and safety of lersivirine in treatment-naive… 
2012
2012
The Pharmacokinetics of Lersivirine (UK-453,061) and HIV-1 Protease Inhibitor Coadministration in Healthy Subjects
Objective:Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type… 
Review
2012
Review
2012
The HIV-1 non-nucleoside reverse transcriptase inhibitors (part V): capravirine and its analogues.
Capravirine (S-1153, AG1549), a 1,2,4,5-tetrasubstituted imidazole derivative, was firstly reported by the Shionogi company to… 
2009
2009
Species differences in the multiple-dose pharmacokinetics of the non-nucleoside reverse transcriptase inhibitor (NNRTI) UK-453,061 in animals and man: implications for safety considerations
The requirements for safe testing of pharmaceuticals in humans places substantial emphasis on the translation of safety testing… 
2008
2008
The rise of second-generation non-nucleoside reverse transcriptase inhibitors: Etravirine, rilpivirine, UK-453061 and RDEA-806
2008
2008
Highlights of the Society for Medicines
The discovery of new therapies for the treatment of delayed gastric emptying represents an opportunity to offer improved… 
2008
2008
The Effect of UGT2B7 Inhibition on the Steady-State Pharmacokinetics of UK-453,061 after Multiple-Dose Administration in Healthy Male Subjects
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