Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

UK 453,061

Known as: UK453061, UK 453061, UK-453061 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
OBJECTIVE A 96-week clinical study was planned to estimate the antiviral activity and safety of lersivirine in treatment-naive… Expand
Is this relevant?
2012
2012
AIMS To investigate the effect of inhibitors of cytochrome P450 (CYP) 3A4 and glucuronidation (UGT2B7) on the pharmacokinetics of… Expand
Is this relevant?
2010
2010
The nonnucleoside reverse transcriptase inhibitors (NNRTIs) are key components of highly active antiretroviral therapy (HAART… Expand
Is this relevant?
2010
2010
Lersivirine [UK-453,061, 5-((3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl)oxy)benzene-1,3-dicarbonitrile] is a next… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2010
2010
Lersivirine (UK-453,061) is a next-generation non-nucleoside reverse transcriptase inhibitor, with a unique binding interaction… Expand
Is this relevant?
2009
2009
OBJECTIVE To investigate the effects on viral load and assess dose-response relationships, pharmacokinetics, safety and… Expand
Is this relevant?
2009
2009
We prepared three discreet cohorts of potent non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) based on the recently… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
2009
2009
The requirements for safe testing of pharmaceuticals in humans places substantial emphasis on the translation of safety testing… Expand
Is this relevant?
2008
2008
1. UK-453,061 is a novel second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Following intravenous bolus… Expand
Is this relevant?
2008
2008
The discovery of new therapies for the treatment of delayed gastric emptying represents an opportunity to offer improved… Expand
Is this relevant?