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UIMC1 gene

Known as: UBIQUITIN INTERACTION MOTIF-CONTAINING PROTEIN 1, UIMC1, RECEPTOR-ASSOCIATED PROTEIN, 80-KD 
This gene is involved in ubiquitin binding and DNA damage responses.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
To rescue collapsed replication forks cells utilize homologous recombination (HR)-mediated mechanisms to avoid the induction of… Expand
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Highly Cited
2012
Highly Cited
2012
DNA repair proteins find sites of damage marked by hybrid SUMO-ubiquitin chains. Hybrid Chains Mark the Spot Posttranslational… Expand
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Highly Cited
2009
Highly Cited
2009
Linkage-specific polyubiquitin recognition is thought to make possible the diverse set of functional outcomes associated with… Expand
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Highly Cited
2009
Highly Cited
2009
Age at menarche and age at natural menopause are associated with causes of substantial morbidity and mortality such as breast… Expand
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Highly Cited
2009
Highly Cited
2009
RAP80 has a key role in the recruitment of the Abraxas-BRCC36-BRCA1-BARD1 complex to DNA-damage foci for DNA repair through… Expand
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Highly Cited
2007
Highly Cited
2007
The Brca1 A complex contains Brca1/Bard1, Abraxas, Rap80, and Brcc36; however, with the exception of the Brca1–Abraxas… Expand
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Highly Cited
2007
Highly Cited
2007
Mutations affecting the BRCT domains of the breast cancer–associated tumor suppressor BRCA1 disrupt the recruitment of this… Expand
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Highly Cited
2007
Highly Cited
2007
The BRCT repeats of the breast and ovarian cancer predisposition protein BRCA1 are essential for tumor suppression… Expand
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Highly Cited
2007
Highly Cited
2007
Mutations in the breast cancer susceptibility gene 1 (BRCA1) are associated with an increased risk of breast and ovarian cancers… Expand
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Highly Cited
2007
Highly Cited
2007
In this study, we examine the potential role of receptor-associated protein 80 (RAP80), a nuclear protein containing two… Expand
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