UIMC1 gene

Known as: UBIQUITIN INTERACTION MOTIF-CONTAINING PROTEIN 1, UIMC1, RECEPTOR-ASSOCIATED PROTEIN, 80-KD 
This gene is involved in ubiquitin binding and DNA damage responses.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
051020022017

Papers overview

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2015
2015
The faithful repair of DNA double-strand breaks (DSBs) is essential to safeguard genome stability. DSBs elicit a signaling… (More)
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2012
Highly Cited
2012
The DNA repair function of the breast cancer susceptibility protein BRCA1 depends in part on its interaction with RAP80, which… (More)
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2012
Highly Cited
2012
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wide association studies (GWAS… (More)
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2011
2011
The cellular response to DNA damage is essential for maintenance of genomic stability. MDC1 is a key member of the DNA damage… (More)
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2009
Highly Cited
2009
Linkage-specific polyubiquitin recognition is thought to make possible the diverse set of functional outcomes associated with… (More)
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2009
Highly Cited
2009
Age at menarche and age at natural menopause are associated with causes of substantial morbidity and mortality such as breast… (More)
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2007
Highly Cited
2007
Mutations affecting the BRCT domains of the breast cancer-associated tumor suppressor BRCA1 disrupt the recruitment of this… (More)
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2007
Highly Cited
2007
The BRCT repeats of the breast and ovarian cancer predisposition protein BRCA1 are essential for tumor suppression… (More)
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2007
Highly Cited
2007
Mutations in the breast cancer susceptibility gene 1 (BRCA1) are associated with an increased risk of breast and ovarian cancers… (More)
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2002
2002
In this study, we describe the characterization of a novel nuclear protein, referred to as RAP80. The RAP80 cDNA was cloned from… (More)
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