UGT1A4 gene

Known as: UDP glucuronosyltransferase family 1 member A4, UGT1D, UDP Glucuronosyltransferase 1 Family, Polypeptide A4 Gene 
This gene is involved in xenobiotic metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UDP-glucuronosyltransferases (UGTs) catalyze glucuronidation of a variety of xenobiotics and endobiotics. UGTs are divided into… (More)
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2007
2007
Protein-protein interactions between human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A4, and UGT1A6 were investigated using… (More)
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2007
2007
UDP-glucuronosyltransferases (UGTs) are membrane-bound proteins localized to the endoplasmic reticulum and catalyze the formation… (More)
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2006
2006
Tamoxifen (TAM) is an antiestrogen widely used in the treatment and prevention of breast cancer in women. One of the major… (More)
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2005
2005
Nineteen genetic variations, including 11 novel ones, were found in exon 1 and its flanking region of the UDP… (More)
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Highly Cited
2004
Highly Cited
2004
UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection… (More)
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2004
2004
Tamoxifen (TAM), a nonsteroidal antiestrogen, is the most widely used drug for chemotherapy of hormone-dependent breast cancer in… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND AND AIMS The liver represents one of the major sites of human glucuronidation. Many therapeutic drugs are substrates… (More)
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Highly Cited
1999
Highly Cited
1999
Human UDP-glucuronosyltransferases (UGTs) are expressed in a tissue-specific fashion in hepatic and extrahepatic tissues… (More)
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Highly Cited
1998
Highly Cited
1998
Glucuronide conjugation of xenobiotics containing a tertiary amine moiety represents a unique and important metabolic pathway for… (More)
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