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UGT1A4 gene

Known as: UDP glucuronosyltransferase family 1 member A4, UGT1D, UDP Glucuronosyltransferase 1 Family, Polypeptide A4 Gene 
This gene is involved in xenobiotic metabolism.
National Institutes of Health

Related topics

Related topics

4 relations
UDP-Glucuronosyltransferase 1-4bilirubin glucuronoside glucuronosyltransferaseglycosylationxenobiotic metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Correction: Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients
The Funding statement is incorrect. The publisher apologizes for the error. The complete, correct Funding statement is: This work… 
2014
2014
INHIBITORY EFFECTS OF ACTIVE CONSTITUENTS AND EXTRACTS OF ANDROGRAPHIS PANICULATA ON UGT 1 A 1 , UGT 1 A 4 , AND UGT 2 B 7 ENZYME ACTIVITIES
Objective: The present investigation addresses the inhibitory potential of five Andrographis paniculata (AP) extracts of… 
2013
2013
Impact of UGT1A4, UGT2B7, and UGT2B15 pharmacogenetics on tamoxifen (TAM) metabolism.
2588 Background: The aims were to characterize the genetic profiles of UGT1A4, UGT2B7 and UGT2B15in Asian healthy populations… 
2012
2012
Interindividual variation in olanzapine concentration influenced by UGT1A4 L48V polymorphism in serum and upstream FMO polymorphisms in cerebrospinal fluid.
Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used… 
2012
2012
Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients
A high inter-individual variability in the pharmacokinetics of lamotrigine has been observed. Lamotrigine is primarily… 
2012
2012
Abstract 1878: Upregulation of UGT1A4 by fulvestrant: A potential elimination mechanism of anastrazole in breast cancer treatment
The pure antiestrogen, fulvestrant (Faslodex®) has been approved for use in the treatment of postmenopausal patients with hormone… 
2010
2010
Exploration on atypical kinetics of UGT1A1 and UGT1A4
University of Minnesota Ph.D. dissertation. August 2010. Major: Medicinal Chemistry. Advisors: Dr. Rory P. Remmel, and Dr… 
2009
2009
Influence of N-Terminal Domain Histidine and Proline Residues on the Substrate Selectivities of Human UDP-Glucuronosyltransferase 1 A 1 , 1 A 6 , 1 A 9 , 2 B 7 , and 2 B 10
An N-terminal domain histidine [corresponding to position 39 of UDP-glucuronosyltransferase (UGT) 1A1] is conserved in all UGT1A… 
2009
2009
UGT1A1, UGT1A4, UGT1A6 及び UGT2B7 に対する簡便な UDP-glucuronosyltransferase assay の確立
2004
2004
THE ROLE OF THERAPEUTIC DRUG MONITORING IN PATIENT CARE
The dose-response relationship for antiepileptic drugs (AEDs) varies enormously between and within individual patients…