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xenobiotic metabolism

Known as: xenobiotic metabolic process 
The chemical reactions and physical changes involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e. g… 
National Institutes of Health

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AHR wt AlleleAKR1C1 geneAKR1C2 geneAKR1C2 protein, human

Papers overview

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Review
2005
Review
2005
Regulation of xenobiotic metabolism by xenobiotic receptors and cytochrome P450 enzymes
Cytochrome P450 (CYP) enzymes metabolize xenobiotics, exogenous molecules, including drugs, environmental chemicals and… 
2004
2004
Dose- and Time-Dependent Effects of Menadione on Enzymes of Xenobiotic Metabolism in Rat Liver
We studied the effect of synthetic vitamin K analogue menadione on enzymes of xenobiotic metabolism in rat liver (total content… 
1990
1990
[Calcium and vitamin D metabolism and enzymes of xenobiotic metabolism during chronic action of mycotoxins].
Experimental rats received T-2 toxin (0.063 mg/kg), deoxynivalenol (1.6 mg/kg) and aflatoxin B1 (0.008 mg/kg) during 6 months… 
1990
1990
Calcium and vitamin D metabolism and enzymes of xenobiotic metabolism during chronic action of mycotoxins
Experimental rats received T-2 toxin (0.063 mg/kg), deoxynivalenol (1.6 mg/kg) and aflatoxin B1 (0.008 mg/kg) during 6 months… 
1987
1987
In vivo and in vitro effects of amrinone and milrinone on hepatic xenobiotic metabolism in rats.
Studies were performed on the response of hepatic xenobiotic metabolizing enzymes to in vitro and in vivo exposure to amrinone… 
1987
1987
[Changes in the activity of enzyme systems of xenobiotic metabolism at different stages of insect development].
The cytochrome P-450 content, activity of microsomal monooxygenases, nonspecific esterases and glutathione S-transferases were… 
1987
1987
Effect of vitamin A deficiency on surfactants and enzymes of xenobiotic metabolism in the rat lung
: Experiments were conducted on 128 male rats kept on a retinol-deprived diet during 12-14 weeks, that resulted in vitamin A… 
1983
1983
Induction of hepatic cytochrome P-450 and drug metabolism by metyrapone in the rat: relevance to its effects in rat-liver cell culture.
  • B. LakeA. Paine
  • Xenobiotica; the fate of foreign compounds in…
  • 1983
  • Corpus ID: 23569222
The ability of metyrapone to induce hepatic cytochrome P-450 and xenobiotic metabolism in rats and rat hepatocyte culture has… 
1982
1982
Dietary cholesterol-induced changes of xenobiotic metabolism in liver. I. Influence of xenobiotic administration on hepatic membrane structure.
We have studied the effects of dietary lipids on the structure and function of hepatic endoplasmic reticulum by feeding rats… 
1979
1979
The induction of hepatic and extrahepatic xenobiotic metabolism in the rat and ferret by a polychlorinated biphenyl mixture (Aroclor 1254).
1. The effect of a single i.p. dose (500 mg/kg) of a polychlorinated biphenyl mixture (Aroclor 1254) on hepatic and extrahepatic…