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UDP-Glucuronosyltransferase 1-4

Known as: UGT1-04, Bilirubin UDP-Glucuronosyltransferase Isozyme 2, UDPGT 1-4 
UDP-glucuronosyltransferase 1-4 (534 aa, ~60 kDa) is encoded by the human UGT1A4 gene. This protein is involved in glucuronidation of toxins.
National Institutes of Health

Papers overview

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2000
2000
Editor—Crigler-Najjar syndromes (CN, MIM 218800) are inborn errors of metabolism characterised by unconjugated… Expand
1998
1998
Publisher Summary All organisms are exposed to a number of chemical compounds that are toxic were it not for metabolic mechanisms… Expand
Highly Cited
1996
Highly Cited
1996
  • M. Green, T. Tephly
  • Drug metabolism and disposition: the biological…
  • 1996
  • Corpus ID: 23524691
Glucuronide conjugation of tertiary amine xenobiotics represents a unique and important metabolic pathway for these compounds in… Expand
Highly Cited
1995
Highly Cited
1995
In humans, the metabolism of a number of tertiary amine-containing pharmacological agents to quaternary ammonium-linked… Expand
Highly Cited
1994
Highly Cited
1994
ABSTRACT: Crigler-Najjar syndrome (CN) type I, which is characterized by the complete absence of bilirubin uridine 5'-diphosphate… Expand
  • table 1
  • table 2
  • figure I
Highly Cited
1993
Highly Cited
1993
Crigler-Najjar syndrome (CN) type II is characterized by severe chronic nonhemolytic unconjugated hyperbilirubinemia due to… Expand
Highly Cited
1993
Highly Cited
1993
Crigler-Najjar syndrome is an inborn error of metabolism that is characterized by severe unconjugated hyperbilirubinemia. The… Expand