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UGGT1 gene

Known as: UDP-glucose glycoprotein glucosyltransferase 1, UGGT1, UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases.
Uridine diphosphate (UDP)-glucose:glycoprotein glucosyltransferase (UGGT) 1 is a soluble protein residing in the endoplasmic… 
Review
2015
Review
2015
Functional analysis of endoplasmic reticulum glucosyltransferase (UGGT): Synthetic chemistry's initiative in glycobiology.
2015
2015
Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
Although UDP-glucuronosyltransferases (UGTs) are important phase II drug-metabolizing enzymes, they are also involved in the… 
Highly Cited
2014
Highly Cited
2014
Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active.
Being recognized as an important constituent of the glycoprotein folding cycle, uridine diphosphate-glucose:glycoprotein… 
2014
2014
Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice
UDP-glucuronosyltransferases (UGTs) are phase II drug-metabolizing enzymes that catalyze glucuronidation of various drugs… 
2013
2013
UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum
The N-glycans promote solubility in the ER even for mutant glycoproteins, such as mutant α1-antitrypsin. This study shows that… 
2013
2013
Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes
Uridine 5′‐diphosphate‐glucuronosyltransferases (UGTs) are phase II drug‐metabolizing enzymes that catalyze glucuronidation of… 
Highly Cited
2003
Highly Cited
2003
The Noncatalytic Portion of Human UDP-glucose:Glycoprotein Glucosyltransferase I Confers UDP-glucose Binding and Transferase Function to the Catalytic Domain*
The eukaryotic cell monitors the fidelity of protein folding in the endoplasmic reticulum and only permits properly folded and/or… 
Highly Cited
2000
Highly Cited
2000
Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that operates as a… 
1998
1998
Functional expression of the human UDP-galactose transporters in the yeast Saccharomyces cerevisiae.
We describe the functional expression of the putative human Golgi UDP-galactose transporters (hUGT1 and hUGT2) in the yeast… 
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