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p62/SQSTM1/A170 is a multimodular protein that is found in ubiquitin-positive inclusions associated with neurodegenerative… Expand Ubiquilins (UBQLNs) are adaptor proteins thought to deliver ubiquitinated substrates to proteasomes. Here, we show a role for… Expand Ubiquilin/PLIC proteins belong to the family of UBL-UBA proteins implicated in the regulation of the ubiquitin-dependent… Expand Although functional diversity in polyubiquitin chain signaling has been ascribed to the ability of differently linked chains to… Expand The ubiquitin-associated (UBA) domain occurs frequently in proteins involved in ubiquitin-dependent signaling pathways. Although… Expand ABSTRACT Ho endonuclease initiates a mating type switch by making a double-strand break at the mating type locus, MAT. Ho is… Expand Huntington's disease is a progressive neurodegenerative disorder that is associated with a CAG repeat expansion in the gene… Expand Paget disease of bone (PDB) is a common disorder characterized by focal and disorganized increases of bone turnover. Genetic… Expand Up-regulation of several stress proteins such as heat-shock proteins and glucose-regulated proteins participate in tolerance… Expand The UBA domain is a motif found in a variety of proteins, some of which are associated with the ubiquitin–proteasome system. We… Expand