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UBA Domain

Known as: Ubiquitin-Associated Domain 
UBA domains are a commonly occurring sequence motif of approximately 45 amino acid residues that are found in diverse proteins involved in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Ubiquilins (UBQLNs) are adaptor proteins thought to deliver ubiquitinated substrates to proteasomes. Here, we show a role for… Expand
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Highly Cited
2008
Highly Cited
2008
Ubiquilin/PLIC proteins belong to the family of UBL-UBA proteins implicated in the regulation of the ubiquitin-dependent… Expand
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Highly Cited
2005
Highly Cited
2005
Although functional diversity in polyubiquitin chain signaling has been ascribed to the ability of differently linked chains to… Expand
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Highly Cited
2005
Highly Cited
2005
The ubiquitin-associated (UBA) domain is one of the most frequently occurring motifs that recognize ubiquitin tags. Dsk2p, a UBA… Expand
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Highly Cited
2004
Highly Cited
2004
Huntington's disease is a progressive neurodegenerative disorder that is associated with a CAG repeat expansion in the gene… Expand
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Highly Cited
2004
Highly Cited
2004
Three novel missense mutations of SQSTM1 were identified in familial PDB, all affecting the UBA domain. Functional and structural… Expand
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Highly Cited
2003
Highly Cited
2003
Mutations in Sequestosome 1 (SQSTM1) have been shown to segregate with familial Paget's disease of bone (PDB). We examined the… Expand
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Highly Cited
2002
Highly Cited
2002
Up-regulation of several stress proteins such as heat-shock proteins and glucose-regulated proteins participate in tolerance… Expand
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Highly Cited
2002
Highly Cited
2002
Paget disease of bone (PDB) is a common disorder characterized by focal and disorganized increases of bone turnover. Genetic… Expand
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Highly Cited
2001
Highly Cited
2001
The UBA domain is a motif found in a variety of proteins, some of which are associated with the ubiquitin–proteasome system. We… Expand
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