Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 218,258,724 papers from all fields of science
Search
Sign In
Create Free Account
LATS2 protein, human
Known as:
Large Tumor Suppressor 2
, Serine/Threonine-Protein Kinase LATS2
, LATS2 Protein
Expand
Serine/threonine-protein kinase LATS2 (1088 aa, ~120 kDa) is encoded by the human LATS2 gene. This protein is involved in both serine/threonine…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
15 relations
Cell Nucleus
Enzyme Gene
G1/S Transition Checkpoint
Homo sapiens
Expand
Broader (2)
Protein-Serine-Threonine Kinases
Tumor Suppressor Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer.
Mingde Huang
,
Jiakai Hou
,
+5 authors
Ming Sun
Molecular Therapy
2017
Corpus ID: 205843360
Highly Cited
2016
Highly Cited
2016
Long Noncoding RNA PVT1 Promotes Non–Small Cell Lung Cancer Cell Proliferation through Epigenetically Regulating LATS2 Expression
L. Wan
,
Ming Sun
,
+6 authors
Zhaoxia Wang
Molecular Cancer Therapeutics
2016
Corpus ID: 23937274
Long noncoding RNAs (lncRNA) are a novel class of transcripts with no protein coding capacity, but with diverse functions in…
Expand
Highly Cited
2016
Highly Cited
2016
Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells
Wei Li
,
Ming Sun
,
+6 authors
Y. Shu
Cell Death and Disease
2016
Corpus ID: 4669989
Recently, long non-coding RNAs (lncRNAs) are identified as new crucial regulators of diverse cellular processes, including cell…
Expand
Highly Cited
2011
Highly Cited
2011
A kinase shRNA screen links LATS2 and the pRB tumor suppressor.
K. Tschöp
,
A. Conery
,
+4 authors
N. Dyson
Genes & Development
2011
Corpus ID: 206228525
pRB-mediated inhibition of cell proliferation is a complex process that depends on the action of many proteins. However, little…
Expand
Highly Cited
2009
Highly Cited
2009
Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma.
Katrin Steinmann
,
A. Sandner
,
U. Schagdarsurengin
,
R. Dammann
Oncology Report
2009
Corpus ID: 22016425
Squamous cell carcinomas of head and neck (HNSCC) are a result of multiple genetic and epigenetic alterations. Epigenetic…
Expand
Highly Cited
2006
Highly Cited
2006
LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis.
Y. Abe
,
Miho Ohsugi
,
K. Haraguchi
,
J. Fujimoto
,
Tadashi Yamamoto
FEBS Letters
2006
Corpus ID: 33590788
LATS2 is a human homolog of Drosophila tumor suppressor lats/warts, and encodes a mitotic kinase whose physiological roles remain…
Expand
Highly Cited
2005
Highly Cited
2005
Down-Regulation of LATS1 and LATS2 mRNA Expression by Promoter Hypermethylation and Its Association with Biologically Aggressive Phenotype in Human Breast Cancers
Yuri Takahashi
,
Y. Miyoshi
,
+4 authors
S. Noguchi
Clinical Cancer Research
2005
Corpus ID: 23415582
Purpose: LATS1 and LATS2 are tumor suppressor genes implicated in the regulation of cell cycle. Methylation status of the…
Expand
Highly Cited
2005
Highly Cited
2005
Downregulation of the large tumor suppressor 2 (LATS2/KPM) gene is associated with poor prognosis in acute lymphoblastic leukemia
A. Jiménez-Velasco
,
J. Román-Gómez
,
+6 authors
A. Heiniger
Leukemia
2005
Corpus ID: 13383237
Downregulation of the large tumor suppressor 2 (LATS2/KPM) gene is associated with poor prognosis in acute lymphoblastic leukemia
Highly Cited
2004
Highly Cited
2004
The centrosomal protein Lats2 is a phosphorylation target of Aurora‐A kinase
S. Toji
,
N. Yabuta
,
+5 authors
H. Nojima
Genes to Cells
2004
Corpus ID: 45300103
Human Lats2, a novel serine/threonine kinase, is a member of the Lats kinase family that includes the Drosophila tumour…
Expand
Highly Cited
2000
Highly Cited
2000
Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.
N. Yabuta
,
Takayuki Fujii
,
+8 authors
Hiroshi Nojima
Genomics
2000
Corpus ID: 264216655
We have cloned and characterized LATS2, a novel mammalian homologue of the Drosophila tumor suppressor gene lats/warts. Northern…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE