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LATS2 protein, human

Known as: Large Tumor Suppressor 2, Serine/Threonine-Protein Kinase LATS2, LATS2 Protein 
Serine/threonine-protein kinase LATS2 (1088 aa, ~120 kDa) is encoded by the human LATS2 gene. This protein is involved in both serine/threonine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Long noncoding RNAs (lncRNA) are a novel class of transcripts with no protein coding capacity, but with diverse functions in… Expand
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Highly Cited
2013
Highly Cited
2013
Dysregulation of microRNAs has a critical role in cancer progression. Here we identify an intronic microRNA, miR-135b that is… Expand
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Highly Cited
2011
Highly Cited
2011
pRB-mediated inhibition of cell proliferation is a complex process that depends on the action of many proteins. However, little… Expand
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Highly Cited
2011
Highly Cited
2011
The Hippo pathway kinase LATS2 promotes contact inhibition of growth. How LATS2 is activated in response to changes in cell… Expand
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Highly Cited
2011
Highly Cited
2011
Malignant mesothelioma (MM) is an aggressive neoplasm associated with asbestos exposure. We carried out genome-wide array-based… Expand
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Highly Cited
2010
Highly Cited
2010
MicroRNAs (miRNAs) regulate gene expression. It has been suggested that obtaining miRNA expression profiles can improve… Expand
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Highly Cited
2009
Highly Cited
2009
LATS2 is a member of the LATS tumor suppressor family. It has been implicated in regulation of the cell cycle and apoptosis… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: LATS1 and LATS2 are tumor suppressor genes implicated in the regulation of cell cycle. Methylation status of the… Expand
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Highly Cited
2005
Highly Cited
2005
Originally identified in Drosophila melanogaster, the Warts(Wts)/Lats protein kinase has been proposed to function with two other… Expand
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Highly Cited
2004
Highly Cited
2004
Human Lats2, a novel serine/threonine kinase, is a member of the Lats kinase family that includes the Drosophila tumour… Expand
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