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U 74500A

Known as: Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(3,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, hydrochloride, (16alpha)-, U-74500A, U74500A 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Anti-Ulcer AgentAntioxidantsImmunosuppressive AgentsPregnatrienes
U 74500EU74500

Papers overview

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2004
2004
The British Journal of Surgery digest
  • J. Farndon
  • Surgery today (Print)
  • 2004
  • Corpus ID: 38597070
Greater understanding of the mechanisms of injury induced after reperfusion for ischemia may help the success rate of… 
1999
1999
Inhibition of lipid peroxidation with the lazaroid U74500A attenuates ischemia-reperfusion injury in a canine orthotopic heart transplantation model
1998
1998
Role of Postischemic Treatment with U-74500A for Prevention of Ischemia and Reperfusion Injury of the Canine Liver
1995
1995
Novel 21‐Aminosteroidlike Compounds Prevent Iron‐Induced Free Radical‐Mediated Injury to Vascular Endothelial Cells
Free radicals appear to play a major role in the reperfusion injury of the myocardium. Iron chelators and antioxidants can… 
1995
1995
Antiperoxidative effects of platelet activating factor antagonists against iron-dependent lipid peroxidation in murine ventricular membranes.
Platelet activating factor (PAF) antagonists have been recently documented to possess beneficial effects on ischemia and ischemia… 
1994
1994
Role of lipid mediators in the pathogenesis of skeletal muscle infarction and oedema during reperfusion after ischaemia
During revascularization of skeletal muscle lipid mediators are released that may have a role in the pathogenesis of reperfusion…