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U-50488

Known as: U 50,488H, U 50488H, U-50,488H 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Analgesics, Non-NarcoticAntihypertensive AgentsPyrrolidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
&kgr;-Opioid Receptors Mediate Cardioprotection by Remote Preconditioning
Background:Remote preconditioning is known to be cardioprotective, but the exact mechanism has not been fully elucidated. The… 
Highly Cited
2002
Highly Cited
2002
Functional Effects of Systemically Administered Agonists and Antagonists of , , and Opioid Receptor Subtypes on Body Temperature in Mice
We have investigated the roles of peripheral and central , , and opioid receptors and their subtypes in opioid-induced… 
Highly Cited
2001
Highly Cited
2001
Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats.
Two series of experiments were performed in the isolated perfused rat heart to determine the role of kappa- and delta-opioid… 
Highly Cited
1999
Highly Cited
1999
Dynorphin selectively augments the M-current in hippocampal CA1 neurons by an opiate receptor mechanism.
Most electrophysiological studies of opioids on hippocampal principal neurons have found indirect actions, usually through… 
Highly Cited
1993
Highly Cited
1993
Opioid actions on neurons of rat lateral amygdala in vitro
Highly Cited
1992
Highly Cited
1992
Cardiovascular actions of the κ‐agonist, U‐50,488H, in the absence and presence of opioid receptor blockade
1 The cardiovascular actions of U‐50,488H, a κ‐receptor agonist, were studied in rat isolated perfused hearts, and in… 
Highly Cited
1988
Highly Cited
1988
Opioid modulation of non‐cholinergic neural bronchoconstriction in guinea‐pig in vivo
1 Opioid receptors have been demonstrated on sensory fibres in the vagus nerve. Non‐cholinergic (NC) neural bronchoconstriction… 
Highly Cited
1988
Highly Cited
1988
Orally administered kappa as well as mu opiate agonists delay gastrointestinal transit time in the guinea pig.
Highly Cited
1988
Highly Cited
1988
Effect of kappa-opioid receptor agonists on morphine analgesia in morphine-naive and morphine-tolerant rats.
1985
1985
Effects of kappa opiate agonists on palatable food consumption in non-deprived rats, with and without food preloads
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