Skip to search formSkip to main contentSkip to account menu

U 0521

Known as: 1-(3,4-dihydroxyphenyl)-2-methyl-1-propanone, U-0521, U0521 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Propiophenones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
The influence of block of catechol-O-methyl transferase on the sensitivity of isolated organs to catecholamines
SummaryThe sensitivity of various isolated organs to catecholamines was tested before and after block of catechol-O-methyl… 
2004
2004
The distribution of 3H-(±)noradrenaline in rabbit aortic strips after inhibition of the noradrenaline-metabolizing enzymes
SummaryRabbit aortic strips (nerve-free, reserpinepretreated or normal) whose noradrenaline-metabolizing enzymes were inhibited… 
Highly Cited
2004
Highly Cited
2004
Extraneuronal removal, accumulation and O-methylation of isoprenaline in the perfused heart
Summary1.Isolated rat and guinea-pig hearts were perfused with 0.95 μM (±)-isoprenaline or 3H(±)-isoprenaline, a catecholamine… 
1996
1996
Comparison of post-junctional α-adrenoceptors in iris dilator muscle of humans, and albino and pigmented rabbits
The relative potency of α-adrenoceptor agonists and the dissociation constants of competitive antagonists were studied to… 
1987
1987
Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521.
1980
1980
The fate of isoprenaline after inhibition of O-methylation and of extraneuronal uptake.
1979
1979
EFFECTS OF UPTAKE INHIBITORS ON RESPONSES OF SHEEP CORONARY ARTERIES TO CATECHOLAMINES AND SYMPATHETIC NERVE STIMULATION
1 Transmural stimulation of intrinsic sympathetic nerves and exogenous catecholamines produce β1‐adrenoceptor mediated relaxant… 
1978
1978
The influence of monoamine oxidase and catechol-O-methyl transferase on the distribution of 3H-(±)-noradrenaline in rabbit aortic strips
Summary1.Rabbit aortic strips were incubated with 1.18 μM 3H-(±)-noradrenaline for 30 min, and the accumulation of noradrenaline… 
1977
1977
Activation of myocardial β-adrenoceptors by the nitrogen-free low affinity ligand 3′,4′-dihydroxy-α-methylpropiophenone (U-0521)
SummaryThe effect of 3′,4′-dihydroxy-α-methylpropiophenone (U-0521) on the rate of spontaneously contracting cultured rat heart… 
1976
1976
The effect of inhibitors of extraneuronal uptake on the distribution of 3H-(±)noradrenaline in nerve-free rabbit aortic strips
Summary1.Nerve-free rabbit aortic strips were exposed to 1.18 μM 3H-(±)noradrenaline for 30 min. When either MAO or COMT was… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)