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U 0521

Known as: 1-(3,4-dihydroxyphenyl)-2-methyl-1-propanone, U-0521, U0521 
 
National Institutes of Health

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1987
1987
[18F]-6-Fluoro-L-DOPA ([18F]DOPA), a tracer for cerebral dopamine in studies utilizing positron emission tomography (PET), is… Expand
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1983
1983
SummaryThe properties of two inhibitors of catechol-O-methyltransferase (COMT), U-0521 and tropolone acetamide, were compared in… Expand
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1983
1983
1--Progesterone, testosterone (40 microM), cortisol and cortisol hemisuccinate (80 microM) caused 6-8 fold potentiations of… Expand
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1982
1982
The effects of the catechol-O-methyltransferase (COMT) inhibitor 3',4'-dihydroxy-2-methyl-propriophenone (U-0521) were studied in… Expand
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1979
1979
1. Transmural stimulation of intrinsic sympathetic nerves and exogenous catecholamines produce beta 1-adrenoceptor mediated… Expand
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1978
1978
Summary1.Rat hearts were perfused with 50–2000 μM 3H-(−)-noradrenaline in the presence of 14C-sorbitol (to measure the… Expand
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1978
1978
Summary1.Hearts were obtained from reserpine-pretreated rats and perfused with 0.95 μM 3H-(−)-noradrenaline. The rate of removal… Expand
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1976
1976
SummaryRabbit aortic strips (nerve-free, reserpinepretreated or normal) whose noradrenaline-metabolizing enzymes were inhibited… Expand
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1974
1974
Summary1.Isolated rat and guinea-pig hearts were perfused with 0.95 μM (±)-isoprenaline or 3H(±)-isoprenaline, a catecholamine… Expand
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1967
1967
A competitive inhibitor of catechol-O-methyl transferase (COMT), 39,49-dihydroxy-α-methyl propiophenone (U-0521), was found to… Expand
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