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Tropoelastin

Known as: Tropoelastin [Chemical/Ingredient] 
A salt-soluble precursor of elastin. Lysyl oxidase is instrumental in converting it to elastin in connective tissue.
National Institutes of Health

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ELN geneIn BloodProcess of secretionagonists

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Tropoelastin b

Papers overview

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2008
2008
Characterization of the molecular interaction between tropoelastin and DANCE/fibulin-5.
Fibulin-5 is believed to play an important role in the elastic fiber formation. The present experiments were carried out to… 
Highly Cited
2004
Highly Cited
2004
Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin.
Tropoelastin is the soluble precursor of the essential resilient connective tissue protein elastin. We examined the binding of… 
2004
2004
Tropoelastin inhibits vascular calcification via 67-kDa elastin binding protein in cultured bovine aortic smooth muscle cells.
In cases of vascular calcification, the expression of tropoelastin is down-regulated, which most likely decreases elastic fiber… 
2001
2001
Building Elastin. Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic rat-1 fibroblasts as a source for lysyl oxidase.
The purpose of this study was to assess the feasibility of crosslinking exogenously produced tropoelastin, the precursor of… 
1992
1992
Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism.
Expression of tropoelastin, the principal precursor of elastic fibers, is tissue-specific and is limited to a brief developmental… 
Highly Cited
1991
Highly Cited
1991
Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype.
1991
1991
Polyclonal antibodies to tropoelastin and the specific detection and measurement of tropoelastin in vitro.
Because tropoelastin is difficult to purify, most antibodies to elastin are raised against the insoluble form of the molecule… 
1991
1991
Developmental changes in tropoelastin mRNA levels in rat lung: evaluation by in situ hybridization.
Alveolarization of the immature lung is thought to be influenced by the presence of elastic fibers that could provide structural… 
Highly Cited
1981
Highly Cited
1981
Modulation of tropoelastin production and elastin messenger ribonucleic acid activity in developing sheep lung.
During fetal development of the sheep lung, elastin content continually increases. For examination of the processes controlling… 
1974
1974
Structural studies on cross-linked regions of elastin.
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