Trisomy 21

A chromosomal abnormality consisting of the presence of a third copy of chromosome 21 in somatic cells.
National Institutes of Health

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Topic mentions per year

1988-2016
012319882016

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2016
2016
Chromosomal aneuploidy and specific gene mutations are recognized early hallmarks of many oncogenic processes. However, the net… (More)
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2015
2015
Many stillbirths result from pregnancy complications, whose root cause is abnormal development and function of the placenta [1… (More)
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2012
2012
Trisomy 21 is associated with hematopoietic abnormalities in the fetal liver, a preleukemic condition termed transient… (More)
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2011
2011
BACKGROUND Trisomy 21 is the most common chromosomal aberration in live births. Some efforts have been made to develop… (More)
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2003
2003
Spontaneous transformation of essential thrombocythaemia (ET) into acute leukaemia is rare. We describe a case of ET that… (More)
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2000
2000
Trisomy 21 (Down syndrome) is the most common chromosomal abnormality associated with mental retardation in humans. Sim2, a human… (More)
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1989
1989
To evaluate the potential of using fluorescence flow cytometry (FFC) in the diagnosis of Down's syndrome we analysed a series of… (More)
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1989
1989
Lymphocyte function associated antigen 1 (LFA-1) is a heterodimeric leucocyte adhesion molecule comprising non-covalently… (More)
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1988
1988
Chromosomal aneuploidy is usually identified by cytogenetic methods. However, for some purposes it would be desirable to have an… (More)
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1988
1988
In this report we present the autopsy findings of acute megakaryoblastic leukemia with tumor formation in a 2-year-old female… (More)
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