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Trisomy 21

A chromosomal abnormality consisting of the presence of a third copy of chromosome 21 in somatic cells.
National Institutes of Health

Papers overview

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2018
2018
Trisomy 21 (T21) is the most prevalent human chromosomal disorder, causing a range of cardiovascular, musculoskeletal, and… Expand
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2016
2016
Chromosomal aneuploidy and specific gene mutations are recognized early hallmarks of many oncogenic processes. However, the net… Expand
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2014
2014
  • Yinyin Xia, Yu‑Bing Ding, +6 authors Ying‑Xiong Wang
  • Molecular medicine reports
  • 2014
Trisomy 21 is a chromosomal condition caused by the presence of all or part of an extra 21st chromosome. There has been limited… Expand
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2014
2014
OBJECTIVE Trisomy 21 and trisomy 18 are the two most common chromosomal anomalies in live births. To find new biomarkers for… Expand
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2011
2011
BACKGROUND Trisomy 21 is the most common chromosomal aberration in live births. Some efforts have been made to develop… Expand
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2011
2011
Although aneuploidies are common structural chromosomal abnormalities, double aneuploidies involving chromosomes 21 and Y are… Expand
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2009
2009
Trisomy 21 is the most common chromosomal abnormality among persons with intellectual disability, with a live birth rate of 1 in… Expand
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2003
2003
Spontaneous transformation of essential thrombocythaemia (ET) into acute leukaemia is rare. We describe a case of ET that… Expand
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1999
1999
OBJECTIVE To evaluate the risk of recurrence of fetal chromosomal aberrations in women who had offspring with numeric chromosomal… Expand
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1998
1998
An analysis of 190 pedigrees with Trisomy 21 suggests a cytoplasmic predisposition for the inheritance of Down syndrome and an… Expand
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