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Trifluperidol

Known as: 1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1-piperidinyl)-, Trifluperidol [Chemical/Ingredient] 
A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA… Expand
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND Limited information is available on whether antipsychotics prescribed in pregnancy are associated with increased risks… Expand
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2004
2004
Neuroleptics penetrate into the brain, where they act not only on neurons but probably also on glial cells. In the available… Expand
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Highly Cited
1997
Highly Cited
1997
Recent studies propose that sigma site ligands antagonize N-methyl-D-aspartate (NMDA) receptors by either direct, or indirect… Expand
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1997
1997
[3H]TCP and [3H]ifenprodil binding to N-methyl-D-aspartate (NMDA) receptors in rat forebrain membranes was used to compare the… Expand
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Highly Cited
1995
Highly Cited
1995
The morphological effects of several neuroleptics as well as other novel and prototypic sigma ligands were examined by addition… Expand
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Highly Cited
1986
Highly Cited
1986
The effects of psychotropic compounds on grooming and burying were compared in mice. Burying behaviour was provoked by glass… Expand
Highly Cited
1981
Highly Cited
1981
The spontaneous locomotor activity of mice, recorded in the first 20 min period after placement in individual cages fitted with… Expand
1976
1976
Abstract The time-course of the development of catalepsy was well correlated with that of a decrease in dopamine in the corpus… Expand
Highly Cited
1967
Highly Cited
1967
Abstract The excretion pattern over a 96 hour period and the metabolic pathway of specifically tritium-labelled haloperidol and 9… Expand
Review
1965
Review
1965
  • P. Janssen
  • International review of neurobiology
  • 1965
  • Corpus ID: 20997660
Publisher Summary This chapter discusses the evolution of two butyrophenones—namely, haloperidol and trifluperidol, from… Expand