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Trifluperidol

Known as: 1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1-piperidinyl)-, Trifluperidol [Chemical/Ingredient] 
A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

Antipsychotic AgentsDopamine Antagonists

Narrower (3)

ID 4708Trisedilclofluperol
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Re-evaluation of in vivo selectivity of [(11)C]SA4503 to σ(1) receptors in the brain: contributions of emopamil binding protein.
Highly Cited
2010
Highly Cited
2010
In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange
The neurotoxic side effects observed for the neuroleptic agent haloperidol have been associated with its pyridinium metabolite… 
2004
2004
Effects of haloperidol and trifluperidol on operant behavior in the rat
SummaryThe effects of trifluperidol (20 to 80 μg/kg), haloperidol (40 to 160μg/ kg) and caffeine (10 mg/kg) on a fixed-ratio… 
1986
1986
Effects of antiglaucoma drugs on the blood flow in rabbit eyes.
Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to… 
1983
1983
Neuroleptics have identical potencies in human brain limbic and putamen regions.
Highly Cited
1981
Highly Cited
1981
Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice.
1977
1977
Effects of the hypocholesteremic agent trifluperidol on the sterol, steryl ester, and fatty acid metabolism of Saccharomyces cerevisiae
Trifluperidol (TFP), at a concentration of 100 muM, inhibited the 24-h growth of Saccharomyces cerevisiae by about 30%. Effects… 
1971
1971
Analytical and pharmacokinetic studies on butyrophenones.
1968
1968
Trifluperidol and cholesterol in man
Trifluperidol, a butyrophenone compound with antipsychotic properties, was studied for its behavioral and hypocholesterolemic… 
1963
1963
TRIFLUPERIDOL: A BUTYROPHENONE DERIVATIVE.
Under double-blind conditions, the effects of trifluperidol, one of the butyrophenone derivatives, were contrasted with the… 
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