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Trichodermin

Known as: Trichodermin [Chemical/Ingredient], Trichothec-9-en-4-ol, 12,13-epoxy-, acetate, (4beta)- 
Antifungal metabolite from several fungi, mainly Trichoderma viride; inhibits protein synthesis by binding to ribosomes; proposed as antifungal and… Expand
National Institutes of Health

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In BloodTrichodermolagonistsanalogs & derivatives
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Papers overview

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2011
2011
Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum.
Trichoderma brevicompactum produces trichodermin, a simple trichothecene-type toxin that shares the first steps of the… Expand
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2011
2011
Overexpression of the Trichoderma brevicompactum tri5 Gene: Effect on the Expression of the Trichodermin Biosynthetic Genes and on Tomato Seedlings
Trichoderma brevicompactum IBT 40841 produces trichodermin, a trichothecene-type toxin that shares most of the steps of its… Expand
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2005
2005
Trichothecene production by Trichoderma brevicompactum.
Trichoderma brevicompactum, T. viride, T. harzianum, T. atroviride, T. longibrachiatum, T. erinaceum, T. citrinoviride, and… Expand
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Highly Cited
1990
Highly Cited
1990
Coaggregation of Streptococcus sanguis and other streptococci with Candida albicans.
Thirteen strains of viridans group streptococci and two strains of other streptococci were tested for coaggregation with Candida… Expand
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1988
1988
Inhibition of 3H-leucine incorporation by trichothecene mycotoxins in maize and wheat tissue
Deoxynivalenol and T-2 toxin inhibit protein synthesis in wheat and maize, hosts for trichothecene-producing strains of… Expand
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1981
1981
Cloning of yeast gene for trichodermin resistance and ribosomal protein L3.
Yeast cells sensitive to the eukaryotic protein synthesis inhibitor trichodermin have been transformed with autonomously… Expand
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Highly Cited
1980
Highly Cited
1980
Germ tube induction in Candida albicans.
A reproducible and simple system for the production of germ tubes from yeast cells of Candida albicans using glucose and… Expand
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Highly Cited
1974
Highly Cited
1974
Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins.
The 12,13-epoxytrichothecenes, a group of sesquiterpenoid fungal antibiotics, inhibit protein synthesis in eukaryotic cells but… Expand
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1974
1974
Binding of trichodermin to mammalian ribosomes and its inhibition by other 12,13-epoxytrichothecenes
SummaryTrichodermin binds to ribosomes from rabbit reticulocyte polysomes with an apparent Ka of 9.2 × 105 and with a maximum… Expand
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1973
1973
The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes.
Abstract We have studied the effects of a number of sesquiterpene antibiotics of the trichodermin group on different steps of the… Expand
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