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Trichodermin

Known as: Trichodermin [Chemical/Ingredient], Trichothec-9-en-4-ol, 12,13-epoxy-, acetate, (4beta)- 
Antifungal metabolite from several fungi, mainly Trichoderma viride; inhibits protein synthesis by binding to ribosomes; proposed as antifungal and… Expand
National Institutes of Health

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In BloodTrichodermolagonistsanalogs & derivatives
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum.
Trichoderma brevicompactum produces trichodermin, a simple trichothecene-type toxin that shares the first steps of the… Expand
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Highly Cited
2005
Highly Cited
2005
Trichothecene production by Trichoderma brevicompactum.
Trichoderma brevicompactum, T. viride, T. harzianum, T. atroviride, T. longibrachiatum, T. erinaceum, T. citrinoviride, and… Expand
Highly Cited
1990
Highly Cited
1990
Coaggregation of Streptococcus sanguis and other streptococci with Candida albicans.
Thirteen strains of viridans group streptococci and two strains of other streptococci were tested for coaggregation with Candida… Expand
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1988
1988
Inhibition of 3H-leucine incorporation by trichothecene mycotoxins in maize and wheat tissue
Deoxynivalenol and T-2 toxin inhibit protein synthesis in wheat and maize, hosts for trichothecene-producing strains of… Expand
Highly Cited
1981
Highly Cited
1981
Cloning of yeast gene for trichodermin resistance and ribosomal protein L3.
  • H. Fried, J. Warner
  • Proceedings of the National Academy of Sciences…
  • 1981
    • Corpus ID: 28714360
Yeast cells sensitive to the eukaryotic protein synthesis inhibitor trichodermin have been transformed with autonomously… Expand
1976
1976
Competition between trichodermin and several other sesquiterpene antibiotics for binding to their receptor site(s) on eukaryotic ribosomes.
1. Of the five sesquiterpene antibiotics tested and found to inhibit protein synthesis in yeast spheroplasts, trichothecin… Expand
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Highly Cited
1975
Highly Cited
1975
Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutants.
A spontaneous mutant of Saccharomyces cerevisiae resistant to trichodermin has been isolated. It displays cross resistance both… Expand
1974
1974
Mechanism of action of the mycotoxin trichodermin, a 12,13-epoxytrichothecene.
Trichodermin is a member of a group of closely related compounds-the 12,13-epoxytrichothecenes-that form a medically and… Expand
Highly Cited
1974
Highly Cited
1974
Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins.
The 12,13-epoxytrichothecenes, a group of sesquiterpenoid fungal antibiotics, inhibit protein synthesis in eukaryotic cells but… Expand
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Highly Cited
1973
Highly Cited
1973
The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes.
Abstract We have studied the effects of a number of sesquiterpene antibiotics of the trichodermin group on different steps of the… Expand
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