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Trichodermin

Known as: Trichodermin [Chemical/Ingredient], Trichothec-9-en-4-ol, 12,13-epoxy-, acetate, (4beta)- 
Antifungal metabolite from several fungi, mainly Trichoderma viride; inhibits protein synthesis by binding to ribosomes; proposed as antifungal and… 
National Institutes of Health

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In BloodTrichodermolagonistsanalogs & derivatives

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Papers overview

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1985
1985
Modification of membrane permeability during Semliki Forest virus infection.
Highly Cited
1981
Highly Cited
1981
Cloning of yeast gene for trichodermin resistance and ribosomal protein L3.
Yeast cells sensitive to the eukaryotic protein synthesis inhibitor trichodermin have been transformed with autonomously… 
Highly Cited
1977
Highly Cited
1977
Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebine…
Stable mutants resistant to the protein synthesis inhibitors cryptopleurine and tylocrebine can be isolated in Chinese hamster… 
1976
1976
Competition between trichodermin and several other sesquiterpene antibiotics for binding to their receptor site(s) on eukaryotic ribosomes.
1. Of the five sesquiterpene antibiotics tested and found to inhibit protein synthesis in yeast spheroplasts, trichothecin… 
Highly Cited
1976
Highly Cited
1976
Mechanism of action of the 12,13-epoxytrichothecene, anguidine, an inhibitor of protein synthesis.
Highly Cited
1976
Highly Cited
1976
Mapping of trichodermin resistance in Saccharomyces cerevisiae: a genetic locus for a component of the 60S ribsomal subunit.
Resistance to the protein synthesis inhibitor trichodermin in Saccharomyces cerevisiae has been studied. A single recessive… 
1976
1976
Activities of nucleoprotein particles derived from rat liver ribosome.
1974
1974
Binding of (acetyl-14C)trichodermin to the peptidyl transferase centre of eukaryotic ribosomes.
The antibiotic trichodermin, an inhibitor of the peptidyl transferase centre of eukaryotic ribosomes, was synthesized… 
Highly Cited
1973
Highly Cited
1973
Trichodermin, a possible inhibitor of the termination process of protein synthesis
The mode of action of the antibiotic, trichodermin, on yeast cells has been investigated. Trichodermin specifically inhibits… 
1973
1973
Total synthesis of (+)-trichodermin.
The first total synthesis of a member of the antibiotic trichothecane group of sesquiterpenes, trichodermin (12,13… 
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