Traxoprodil

Known as: (Alpha-S,Beta-S)-4-Hydroxy-Alpha-(P-Hydroxyphenyl)-Beta-Methyl-4-Phenyl-1-Piperidineethanol, 1-Piperidineethanol, 4-Hydroxy-Alpha-(4-Hydroxyphenyl)-Beta-Methyl-4-Phenyl-, (S-(R*,R*))- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
012319932017

Papers overview

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2016
2016
One of the newest substances, whose antidepressant activity was shown is traxoprodil, which is a selective antagonist of the NR2B… (More)
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2012
2012
Polyamines, including spermidine, facilitate seizures by positively modulating N-methyl-d-aspartate receptors (NMDAr). Although… (More)
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2011
2011
BACKGROUND At low dose, the nonselective N-methyl-D-aspartate receptor antagonist ketamine produces potent analgesia. In humans… (More)
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2010
2010
Polyamines, such as spermidine and spermine, have been reported to improve memory retention through the activation of N-methyl-d… (More)
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2007
2007
Disposition of traxoprodil ({1-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethyl]-4-phenyl-piperidin-4-ol}mesylate; TRX), a… (More)
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2007
2007
Development of N-methyl-D-aspartate (NMDA) antagonists for a variety of disorders has been hindered by their production of… (More)
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2006
2006
BACKGROUND Traxoprodil, a substituted 4-phenylpiperidine, is an N-methyl-D-aspartate (NMDA) receptor antagonist that is selective… (More)
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2005
2005
Traumatic brain injury (TBI) remains a major public health problem, and there is a great medical need for a pharmacological… (More)
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2005
2005
We previously reported that the NR2B subunit-selective N-methyl-d-aspartate (NMDA) antagonist Ro 63-1908 produced a marked… (More)
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2003
2003
The excretion, biotransformation, and pharmacokinetics of a selective N-methyl-D-aspartate receptor antagonist, traxoprodil, were… (More)
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