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Thioinosine

Known as: 6-MP riboside, Thioinosine [Chemical/Ingredient], Ribosyl-6-mercaptopurine 
A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (10)

2'-deoxy-6-thioinosine2-fluoro-4-nitrobenzyl mercaptopurine riboside4-nitrobenzylthioinosine5'-isobutylthioinosine

Broader (2)

Antimetabolites, AntineoplasticImmunosuppressive Agents
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function.
BACKGROUND & AIMS Genetic variation of inosine triphosphatase (ITPA) causing an accumulation of inosine triphosphate (ITP) has… 
Highly Cited
2002
Highly Cited
2002
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside
A new synthetic drug, benzamide riboside (BR) exhibited strong oncolytic activity against leukemic cells in the 5–10 μM range… 
Review
1999
Review
1999
Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.
Inosine 5 -monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme for the synthesis of GTP and dGTP. Two isoforms of IMPDH… 
Highly Cited
1996
Highly Cited
1996
Hypoglycaemic effect of AICAriboside in mice
SummaryWe have previously demonstrated that in isolated hepatocytes from fasted rats, AICAriboside (5-amino 4… 
Highly Cited
1987
Highly Cited
1987
The Physiological Basis for Cytokinin Induced Increases in Pod Set in IX93-100 Soybeans.
Previous investigations have shown the feasibility of increasing pod number on legumes by the application of 6-benzylaminopurine… 
Highly Cited
1986
Highly Cited
1986
Monoclonal Antibodies to Plant Growth Regulators: III. Zeatinriboside and Dihydrozeatinriboside.
Four high affinity monoclonal antibodies, which recognize two plant growth regulators from the cytokinin group, namely trans… 
Highly Cited
1984
Highly Cited
1984
Quantitation of cytokinins in biological samples using antibodies against zeatin riboside.
The cross-reactivity of antibodies elicited in rabbits against zeatin riboside, to a wide range of naturally occurring cytokinins… 
1982
1982
Purine catabolism in plants : purification and some properties of inosine nucleosidase from yellow lupin (lupinus luteus L.) seeds.
Inosine nucleosidase (EC 3.2.2.2), the enzyme which hydrolyzes inosine to hypoxanthine and ribose, has been partially purified… 
Highly Cited
1977
Highly Cited
1977
Activation of steroidogenesis and adenylate cyclase by adenosine in adrenal and Leydig tumor cells.
Steroidogenesis by Y-1 adrenal tumor cells in culture is stimulated by ATP, adenyl-5'-yl imidodiphosphate (App(NH)), adenosine 5… 
Highly Cited
1966
Highly Cited
1966
Specificity of adenosine deaminase toward adenosine and 2'-deoxyadenosine analogues.
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