Thioinosine

Known as: 6-MP riboside, Thioinosine [Chemical/Ingredient], Ribosyl-6-mercaptopurine 
A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de… (More)

Topic mentions per year

Topic mentions per year

1956-2017
02419562016

Papers overview

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2006
2006
BACKGROUND Adverse events leading to discontinuation or dose reduction of thiopurine therapy occur in 9-28% of patients with… (More)
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Highly Cited
2002
Highly Cited
2002
Mercaptopurines have been used as anticancer agents for more than 40 years, and most acute lymphoblastic leukemias are treated… (More)
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1999
1999
A reversed-phase high-performance liquid chromatography (HPLC) method was developed to determine 6-mercaptopurine (MP) and seven… (More)
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1996
1996
6-Mercaptopurine riboside (6-MPr) is used as a cytostatic chemotherapeutic. The teratogenic potential in rodents has been well… (More)
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1990
1990
A number of 6-sulfenamide, 6-sulfinamide, and 6-sulfonamide derivatives of 2-aminopurine and certain related purine… (More)
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1982
1982
Inosine nucleosidase (EC 3.2.2.2), the enzyme which hydrolyzes inosine to hypoxanthine and ribose, has been partially purified… (More)
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1981
1981
In an attempt to further define the site of myocardial adenosine formation, isolated guinea pig hearts were perfused with potent… (More)
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1969
1969
been demonstrated. The transfer of pentose from purine nude osides to pyrimidine bases is the subject of this communica tion… (More)
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