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Therapeutic gamma delta T-lymphocytes

Known as: gammadelta T Cells, gd T Cells 
A subset of therapeutic autologous T-lymphocytes that express a T-cell receptor (TCR) composed of one gamma chain and one delta chain, with potential… 
National Institutes of Health

Related topics

Related topics

4 relations
Antigen SensitizationCytotoxic T-LymphocytesT-Cell Activationimmunopotentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
γδ T Lymphocytes Count Is Normal and Expandable in Peripheral Blood of Patients with Follicular Lymphoma, Whereas It Is Decreased in Tumor Lymph Nodes Compared with Inflammatory Lymph Nodes
γδ T lymphocytes are attractive effector cells for immunotherapy. In vitro, they can be expanded and kill efficiently a variety… 
2008
2008
Characterization and TCR variable region gene use of mouse resident nasal γδ T lymphocytes
Tissue‐resident γδ T lymphocytes, such as dendritic epidermal T cells, intestinal intraepithelial lymphocytes (IEL), and resident… 
2007
2007
Human gammadelta T cells modulate the mite allergen-specific T-helper type 2-skewed immunity.
BACKGROUND Gammadelta T cells have been described as one of immune regulators in patients with infection, malignancy, and allergy… 
2007
2007
Two groups of porcine TCRgammadelta+ thymocytes behave and diverge differently.
Developmental pathways of gammadelta T cells are still unknown, largely because of the absence of recognized lineage-specific… 
2002
2002
A Gnotobiotic Transgenic Mouse Model for Studying Interactions between Small Intestinal Enterocytes and Intraepithelial Lymphocytes* 210
The mouse intestinal epithelium undergoes continuous renewal throughout life. Intraepithelial lymphocytes (IELs) represent a… 
2002
2002
Activation-induced Modification in the CD3 Complex of the γδ T Cell Receptor
The T cell antigen receptor complexes expressed on αβ and γδ T cells differ not only in their respective clonotypic heterodimers… 
2002
2002
IL-4 and T Cells Are Required for the Generation of IgG1 Isotype Antibodies Against Cardiolipin1
Infection with Mycobacterium tuberculosis induces Abs against a vast array of mycobacterial lipids and glycolipids. One of the… 
2000
2000
Cytokine profile of draining lymph node lymphocytes in mice grafted with syngeneic keratinocytes expressing human papillomavirus type 16 E7 protein.
Studies on the immune response to human papillomaviruses are compromised by the extreme host and tissue specificity of these… 
1998
1998
Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.
Antigen recognition by T lymphocytes is mediated by cell-surface glycoproteins known as T-cell antigen receptors (TCRs). These… 
1998
1998
Trophoblast IFN-tau differentially induces lymphopenia and neutropenia in lambs.
Type I interferons (IFN), including IFN-alpha and IFN-beta, cause severe lymphopenia, resulting from altered lymphocyte… 
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