Share This Author
Board-invited review: intrauterine growth retardation: implications for the animal sciences.
There is growing evidence that maternal nutritional status can alter the epigenetic state (stable alterations of gene expression through DNA methylation and histone modifications) of the fetal genome, which may provide a molecular mechanism for the role of maternal nutrition on fetal programming and genomic imprinting.
Arginine metabolism and nutrition in growth, health and disease
The results of both experimental and clinical studies indicate that Arg is a nutritionally essential amino acid (AA) for spermatogenesis, embryonic survival, fetal and neonatal growth, as well as maintenance of vascular tone and hemodynamics and novel and effective therapies for obesity, diabetes, and the metabolic syndrome.
Maternal nutrition and fetal development.
There is growing evidence that maternal nutritional status can alter the epigenetic state (stable alterations of gene expression through DNA methylation and histone modifications) of the fetal genome, which may provide a molecular mechanism for the impact of maternal nutrition on both fetal programming and genomic imprinting.
Developmental Biology of Uterine Glands1
That disruption of uterine development during critical organizational periods can alter the functional capacity and embryotrophic potential of the adult uterus reinforces the importance of understanding the developmental biology of uterusine glands.
Triennial Growth Symposium: important roles for L-glutamine in swine nutrition and production.
Dietary supplementation with 1% Gln maintains gut health and prevents intestinal dysfunction in low-birth-weight or early-weaned piglets while increasing their growth performance and survival, and enhances milk production by lactating sows.
Implantation mechanisms: insights from the sheep.
Understanding of the cellular and molecular signals that regulate uterine receptivity and implantation can be used to diagnose and identify causes of recurrent pregnancy loss and to improve pregnancy outcome in domestic animals and humans.
Dietary L-arginine supplementation enhances the reproductive performance of gilts.
- R. D. Mateo, Guoyao Wu, F. Bazer, J. C. Park, I. Shinzato, S. Kim
- Biology, MedicineJournal of NutriLife
- 1 March 2007
Testing the hypothesis that dietary l-arginine supplementation may improve reproductive performance of pregnant gilts provided the first evidence for a marked increase of live-born piglets by 2 per litter through nutritional intervention in gilts.
Comparative aspects of implantation.
There is compelling evidence that uterine receptivity to implantation involves temporal and cell-specific expression of interferon (IFN)-stimulated genes that have many roles including nutrient transport, cellular remodeling, angiogenesis and relaxation of vascular tissues, cell proliferation and migration, establishment of an antiviral state, and protection of conceptus tissues from challenges by the maternal immune cells.
Conceptus signals for establishment and maintenance of pregnancy
Subsequently, sequential, overlapping actions of progesterone, IFN tau, placental lactogen (PL) and growth hormone (GH) comprise a hormonal servomechanism that regulates endometrial gland morphogenesis and terminal differentiated function to maintain pregnancy in sheep.
Establishment of pregnancy in the pig: II. Cellular remodeling of the porcine blastocyst during elongation on day 12 of pregnancy.
- R. Geisert, J. W. Brookbank, R. Roberts, F. Bazer
- Biology, MedicineBiology of Reproduction
- 1 November 1982
The morphology of pig blastocysts changes dramatically just preceding initial attachment of the trophoblast to the uterine epitheliuin, and possible mechanism(s) involved with changes in blastocyst morphology are investigated.