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Telomere Recombination

Known as: Telomere-Telomere Recombination 
Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical on all… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
In human somatic cells or yeast cells lacking telomerase, telomeres are shortened upon each cell division. This gradual… Expand
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Highly Cited
2013
Highly Cited
2013
Although telomeres are heterochromatic, they are transcribed into noncoding telomeric repeat–containing RNA (TERRA). Here we show… Expand
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Highly Cited
2010
Highly Cited
2010
Shelterin is an essential telomeric protein complex that prevents DNA damage signaling and DNA repair at mammalian chromosome… Expand
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Highly Cited
2010
Highly Cited
2010
Exceptional genomic stability is one of the hallmarks of mouse embryonic stem (ES) cells. However, the genes contributing to this… Expand
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Highly Cited
2008
Highly Cited
2008
Dicer initiates RNA interference by generating small RNAs involved in various silencing pathways. Dicer participates in… Expand
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Highly Cited
2007
Highly Cited
2007
Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated… Expand
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Highly Cited
2006
Highly Cited
2006
Here, we describe a role for mammalian DNA methyltransferases (DNMTs) in telomere length control. Mouse embryonic stem (ES) cells… Expand
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Highly Cited
2001
Highly Cited
2001
Immortal human cells maintain their telomeres by two independent mechanisms, a prevalent one dependent on de novo synthesis of… Expand
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Highly Cited
1999
Highly Cited
1999
Many Saccharomyces telomeres bear one or more copies of the repetitive Y' element followed by approximately 350 bp of telomerase… Expand
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Highly Cited
1998
Highly Cited
1998
Telomeres are functionally distinct from ends generated by chromosome breakage, in that telomeres, unlike double-strand breaks… Expand
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