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Telomere Recombination

Known as: Telomere-Telomere Recombination 
Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical on all… 
National Institutes of Health

Related topics

Related topics

5 relations
Cell SurvivalFEN1 geneFEN1 wt AlleleFlap Endonuclease-1

Papers overview

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Highly Cited
2015
Highly Cited
2015
SMARCAL1 maintains telomere integrity during DNA replication
Significance DNA replication is challenged by many sources of stress including DNA damage and difficult-to-replicate DNA… 
Highly Cited
2014
Highly Cited
2014
NuRD–ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination
Alternative lengthening of telomeres (ALT) is a homologous recombination (HR)-dependent mechanism for de novo synthesis of… 
Highly Cited
2009
Highly Cited
2009
Telomere recombination requires the MUS81 endonuclease
Telomerase-negative cancer cells maintain their telomeres through the alternative lengthening of telomeres (ALT) pathway… 
Highly Cited
2008
Highly Cited
2008
Centromere mitotic recombination in mammalian cells
Centromeres are special structures of eukaryotic chromosomes that hold sister chromatid together and ensure proper chromosome… 
Highly Cited
2007
Highly Cited
2007
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated… 
Highly Cited
2006
Highly Cited
2006
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
Here, we describe a role for mammalian DNA methyltransferases (DNMTs) in telomere length control. Mouse embryonic stem (ES) cells… 
2006
2006
Involvement of Topoisomerase III in Telomere-Telomere Recombination*
Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the action of telomerase. In… 
2005
2005
Extrachromosomal Telomeric Circles Contribute to Rad52-, Rad50-, and Polymerase δ-Mediated Telomere-Telomere Recombination in Saccharomyces cerevisiae
ABSTRACT Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the telomerase… 
Highly Cited
2001
Highly Cited
2001
Telomere maintenance by telomerase and by recombination can coexist in human cells.
Immortal human cells maintain their telomeres by two independent mechanisms, a prevalent one dependent on de novo synthesis of… 
Highly Cited
1998
Highly Cited
1998
Telomere maintenance is dependent on activities required for end repair of double-strand breaks
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