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FEN1 wt Allele

Known as: Maturation Factor-1 Gene, DNase IV Gene, RAD2 
Human FEN1 wild-type allele is located in the vicinity of 11q12 and is approximately 5 kb in length. This allele, which encodes flap endonuclease 1… Expand
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
In addition to xeroderma pigmentosum, mutations in the human XPG gene cause early onset Cockayne syndrome (CS). Here, we provide… Expand
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Highly Cited
2001
Highly Cited
2001
Laboratory mice (strain MF1) were used to determine whether sustainable rates of energy intake are limited during lactation. Mice… Expand
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Highly Cited
2000
Highly Cited
2000
The Saccharomyces cerevisiae Dna2, which contains single-stranded DNA-specific endonuclease activity, interacts genetically and… Expand
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Highly Cited
1999
Highly Cited
1999
The RAD2 family of nucleases includes humanXPG (Class I), FEN1 (Class II), andHEX1/hEXO1 (Class III) products gene. These… Expand
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Highly Cited
1999
Highly Cited
1999
The mechanism by which trinucleotide expansion occurs in human genes is not understood. However, it has been hypothesized that… Expand
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Highly Cited
1996
Highly Cited
1996
In Saccharomyces cerevisiae, an HO endonuclease-induced double-strand break can be repaired by at least two pathways of… Expand
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Highly Cited
1996
Highly Cited
1996
Bacteriophage T4 RNase H is a 5' to 3' exonuclease that removes RNA primers from the lagging strand of the DNA replication fork… Expand
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Highly Cited
1995
Highly Cited
1995
HO endonuclease-induced double-strand breaks (DSBs) in the yeast Saccharomyces cerevisiae can be repaired by the process of gap… Expand
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Highly Cited
1994
Highly Cited
1994
Structure-specific nucleases catalyze critical reactions in DNA replication, recombination, and repair. Recently, a structure… Expand
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Highly Cited
1993
Highly Cited
1993
DEFECTS in human DNA repair proteins can give rise to the autosomal recessive disorders xeroderma pigmentosum (XP) and Cockayne's… Expand
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