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FEN1 wt Allele

Known as: Maturation Factor-1 Gene, DNase IV Gene, RAD2 
Human FEN1 wild-type allele is located in the vicinity of 11q12 and is approximately 5 kb in length. This allele, which encodes flap endonuclease 1… 
National Institutes of Health

Related topics

Related topics

7 relations
11q12Base Excision RepairDNA ReplicationDouble Strand Break Repair

Papers overview

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Highly Cited
2005
Highly Cited
2005
Role of the Schizosaccharomyces pombe F-Box DNA Helicase in Processing Recombination Intermediates
ABSTRACT In an effort to identify novel genes involved in recombination repair, we isolated fission yeast Schizosaccharomyces… 
2003
2003
Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability.
1996
1996
Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′- to 3′-Exonuclease/Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1*
The mammalian 5′- to 3′-exonuclease/endonuclease, called RAD2 homologue 1 or flap endonuclease 1, has a unique cleavage activity… 
Highly Cited
1996
Highly Cited
1996
Human RAD2 Homolog 1 5′- to 3′-Exo/Endonuclease Can Efficiently Excise a Displaced DNA Fragment Containing a 5′-Terminal Abasic Lesion by Endonuclease Activity*
Repair of abasic lesions, one of the most common types of damage found in DNA, is crucial to an organism's well-being. Studies in… 
1995
1995
Pulsed-field gel electrophoresis analysis of the repair of psoralen plus UVA induced DNA photoadducts in Saccharomyces cerevisiae.
1992
1992
Sequence of a 10·7 kb segment of yeast chromosome XI identifies the APN1 and the BAF1 loci and reveals one tRNA gene and several new open reading frames including homologs to RAD2 and kinases
We report here the DNA sequence of a segment of chromosome XI of Saccharomyces cerevisiae extending over 10·7 kb. The sequence… 
Highly Cited
1990
Highly Cited
1990
Expression of the yeast PHR1 gene is induced by DNA-damaging agents
The PHR1 gene of Saccharomyces cerevisiae encodes a photolyase which repairs specifically and exclusively pyrimidine dimers, the… 
Highly Cited
1986
Highly Cited
1986
A yeast excision-repair gene is inducible by DNA damaging agents.
Plasmids containing various RAD-lacZ gene fusions were integrated into the chromosome of haploid yeast cells. These integrant… 
Highly Cited
1986
Highly Cited
1986
Nucleotide sequence, transcript mapping, and regulation of the RAD2 gene of Saccharomyces cerevisiae
We determined the nucleotide sequence, mapped the 5' and 3' mRNA termini, and examined the regulation of the RAD2 gene of… 
1985
1985
The RAD2 gene of Saccharomyces cerevisiae: nucleotide sequence and transcript mapping.
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