FEN1 gene

Known as: Flap Structure-Specific Endonuclease 1 Gene, MATURATION FACTOR 1, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE 1 
This gene is involved in DNA replication and repair.
National Institutes of Health

Papers overview

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2012
2012
We propose that cell-cycle-dependent timing of FEN1 nuclease activity is essential for cell-cycle progression and the maintenance… (More)
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Highly Cited
2011
Highly Cited
2011
Flap endonuclease (FEN1), essential for DNA replication and repair, removes RNA and DNA 5' flaps. FEN1 5' nuclease superfamily… (More)
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Highly Cited
2005
Highly Cited
2005
Flap endonuclease-1 (FEN1) is a key enzyme for maintaining genomic stability and replication. Proliferating cell nuclear antigen… (More)
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Highly Cited
2004
Highly Cited
2004
During each yeast cell cycle, approximately 100,000 nicks are generated during lagging-strand DNA replication. Efficient nick… (More)
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Highly Cited
2003
Highly Cited
2003
In the presence of proliferating cell nuclear antigen, yeast DNA polymerase delta (Pol delta) replicated DNA at a rate of 40-60… (More)
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Highly Cited
2002
Highly Cited
2002
Flap endonuclease (Fen1) is required for DNA replication and repair, and defects in the gene encoding Fen1 cause increased… (More)
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Highly Cited
2000
Highly Cited
2000
The murine genes, Foxc1 and Foxc2 (previously, Mf1 and Mfh1), encode forkhead/winged helix transcription factors with virtually… (More)
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Highly Cited
2000
Highly Cited
2000
The FEN1 nuclease functions during Okazaki fragment maturation in the eukaryotic cell. Like many other proliferating cell nuclear… (More)
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Highly Cited
1998
Highly Cited
1998
Mf1 encodes a forkhead/winged helix transcription factor expressed in many embryonic tissues, including prechondrogenic… (More)
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Highly Cited
1977
Highly Cited
1977
Unfertilized mouse oocytes were frozen and stored at --196 degrees C. Immediately after thawing 331 out of 463 MF1 oocytes (71-5… (More)
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