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Tangier Disease

Known as: Thesaurismoses, Cholesterol, High-Density Lipoprotein Deficiency, Tangier Type, alpha lipoprotein deficiency 
An autosomal recessively inherited disorder caused by mutation of ATP-BINDING CASSETTE TRANSPORTERS involved in cellular cholesterol removal (reverse… 
National Institutes of Health

Related topics

Related topics

25 relations
ABCA1 geneATP Binding Cassette Transporter 1AtherosclerosisAutosomal recessive inheritance

Narrower (1)

Tangier Disease Neuropathy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Oral D-4F Causes Formation of Pre-βHigh-Density Lipoprotein and Improves High-Density Lipoprotein–Mediated Cholesterol Efflux and Reverse Cholesterol Transport From Macrophages in Apolipoprotein E…
Background— These studies were designed to determine the mechanism of action of an oral apolipoprotein (apo) A-I mimetic peptide… 
Highly Cited
2003
Highly Cited
2003
Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women. A randomized controlled trial
Review
2001
Review
2001
A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasmin.
The mechanisms by which low-density lipoprotein (LDL) particles undergo oxidative modification to an atherogenic form that is… 
Review
2000
Review
2000
The endotoxin-lipoprotein hypothesis
Highly Cited
1999
Highly Cited
1999
Mutations in the ABC 1 gene in familial HDL deficiency with defective cholesterol efflux
Highly Cited
1994
Highly Cited
1994
Serum Antioxidants and Myocardial Infarction: Are Low Levels of Carotenoids and α‐ Tocopherol Risk Factors for Myocardial Infarction?
BackgroundIn vitro, animal and epidemiological studies suggest that lipoprotein oxidation may play an important role in… 
Review
1990
Review
1990
The antioxidant hypothesis of cardiovascular disease: epidemiology and mechanisms.
Plasma levels of major essential antioxidants were determined in representative random samples of middle-aged men from 16… 
Highly Cited
1982
Highly Cited
1982
Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase.
Highly Cited
1980
Highly Cited
1980
Prevalence of coronary heart disease in the Framingham Offspring Study: role of lipoprotein cholesterols.
Review
1978
Review
1978
Lipoprotein apoprotein metabolism.
The study of the plasma lipoproteins in recent years has significantly broadened our understanding of lipid metabolism and lipid… 
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