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ABCA1 gene

Known as: CERP, ATP-BINDING CASSETTE, SUBFAMILY A, MEMBER 1, ABC TRANSPORTER 1 
This gene plays a role in intracellular cholesterol transport.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
ATP-binding cassette transporter A1 (ABCA1) is a cell membrane protein that exports excess cholesterol from cells to… Expand
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Highly Cited
2007
Highly Cited
2007
HDLs protect against the development of atherosclerosis, but the underlying mechanisms are poorly understood. HDL and its… Expand
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Highly Cited
2007
Highly Cited
2007
Type 2 diabetes is characterized by both peripheral insulin resistance and reduced insulin secretion by β-cells. The reasons for… Expand
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Highly Cited
2002
Highly Cited
2002
The ATP-binding cassette transporter 1 (ABCA1) has recently been identified as a key regulator of high-density lipoprotein (HDL… Expand
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Highly Cited
2002
Highly Cited
2002
The ATP-binding cassette transporter A1 (ABCA1) encodes a membrane protein that promotes cholesterol and phospholipid efflux from… Expand
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Highly Cited
2001
Highly Cited
2001
Previous work has implicated PPAR gamma in the regulation of CD36 expression and macrophage uptake of oxidized LDL (oxLDL). We… Expand
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Highly Cited
2001
Highly Cited
2001
ABCA1, an ATP-binding cassette transporter mutated in Tangier disease, promotes cellular phospholipid and cholesterol efflux by… Expand
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Highly Cited
2000
Highly Cited
2000
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate lipid and glucose metabolism and cellular… Expand
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Highly Cited
2000
Highly Cited
2000
We and others have recently identified mutations in the ABCA1 gene as the underlying cause of Tangier disease (TD) and of a… Expand
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Highly Cited
2000
Highly Cited
2000
Lipid-poor high density lipoprotein apolipoproteins remove cholesterol and phospholipids from cells by an active secretory… Expand
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