ABCA1 gene

Known as: CERP, ATP-BINDING CASSETTE, SUBFAMILY A, MEMBER 1, ABC TRANSPORTER 1 
This gene plays a role in intracellular cholesterol transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05010019762018

Papers overview

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Highly Cited
2004
Highly Cited
2004
ABCA1 is a cholesterol transporter that is widely expressed throughout the body. Outside the central nervous system (CNS), ABCA1… (More)
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Highly Cited
2002
Highly Cited
2002
The ATP-binding cassette transporter A1 (ABCA1) encodes a membrane protein that promotes cholesterol and phospholipid efflux from… (More)
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Highly Cited
2002
Highly Cited
2002
The ATP-binding cassette transporter 1 (ABCA1) has recently been identified as a key regulator of high-density lipoprotein (HDL… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of mutations in the ABCA1 transporter (ABCA1) as the genetic defect in Tangier disease has generated interest in… (More)
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Highly Cited
2001
Highly Cited
2001
Previous work has implicated PPAR gamma in the regulation of CD36 expression and macrophage uptake of oxidized LDL (oxLDL). We… (More)
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Highly Cited
2001
Highly Cited
2001
The discovery of the ABCA1 lipid transporter has generated interest in modulating human plasma HDL levels and atherogenic risk by… (More)
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Highly Cited
2000
Highly Cited
2000
We and others have recently identified mutations in the ABCA1 gene as the underlying cause of Tangier disease (TD) and of a… (More)
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Highly Cited
2000
Highly Cited
2000
Lipid-poor high density lipoprotein apolipoproteins remove cholesterol and phospholipids from cells by an active secretory… (More)
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Highly Cited
1999
Highly Cited
1999
Genes have a major role in the control of high-density lipoprotein (HDL) cholesterol (HDL-C) levels. Here we have identified two… (More)
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Highly Cited
1999
Highly Cited
1999
The ABC1 transporter was identified as the defect in Tangier disease by a combined strategy of gene expression microarray… (More)
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