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Tamoxifen Citrate

Known as: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate (1:1), 1-p-beta-dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene Citrate, Tamoxifen Citrate [Chemical/Ingredient] 
The citrate salt of an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). Tamoxifen competitively inhibits the binding of… 
National Institutes of Health

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Apo-tamoxICI-46474NolvadexSoltamox
CYP2C9 protein, humanCyclophosphamide/Fluorouracil/TamoxifenCytochrome P450 2D6, humanDAVTH protocol

Broader (1)

Tamoxifen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Prescription of tamoxifen for breast cancer prevention by primary care physicians.
BACKGROUND Although tamoxifen citrate has been approved for primary reduction of breast cancer risk since 1998, little is known… 
2004
2004
Phase I Study of percutaneous 4-hydroxy-tamoxifen with analyses of 4-hydroxy-tamoxifen concentrations in breast cancer and normal breast tissue
Abstract4-OH-tamoxifen is an active metabolite of tamoxifen that is detectable in the serum and tumour tissue of patients treated… 
2004
2004
Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice
The non-steroidal antiestrogen tamoxifen (TAM) is successfully used to treat all stages of breast cancer in both pre- and… 
Highly Cited
1999
Highly Cited
1999
Salvage chemotherapy with tamoxifen for recurrent anaplastic astrocytomas.
BACKGROUND A prospective phase 2 study of daily oral tamoxifen citrate in young adults with recurrent anaplastic astrocytomas… 
Highly Cited
1992
Highly Cited
1992
Chemoprevention of MNU-induced mammary tumors in the mature rat by 4-HPR and tamoxifen.
The chemopreventive efficacies of the retinoid all-trans-N-(4-hydroxyphenyl)-retinamide (4-HPR) and the anti-estrogen tamoxifen… 
Highly Cited
1990
Highly Cited
1990
Tamoxifen-associated endometrial carcinoma in postmenopausal breast cancer patients.
Highly Cited
1988
Highly Cited
1988
Paradoxical hypermasculinization of the zebra finch song system by an antiestrogen
1987
1987
Determination of estrogen and androgen receptors in Trichomonas vaginalis and the effects of antihormones.
Highly Cited
1984
Highly Cited
1984
Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching antiestrogen.
We have used a covalently attaching antiestrogen, tamoxifen aziridine [TA; (Z)-(1-[4-(2-[N-aziridinyl] ethoxy)phenyl])1,2… 
1982
1982
Modulation of rat uterine progesterone receptor levels and peroxidase activity by tamoxifen citrate, LY117018, and estradiol.
The biochemical and morphological effects on the immature rat uterus of tamoxifen citrate (TAM) and LY117018 were compared with… 
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