• Publications
  • Influence
The genome of a songbird
The zebra finch is an important model organism in several fields with unique relevance to human neuroscience. Like other songbirds, the zebra finch communicates through learned vocalizations, anExpand
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Tissue-specific expression and regulation of sexually dimorphic genes in mice.
We report a comprehensive analysis of gene expression differences between sexes in multiple somatic tissues of 334 mice derived from an intercross between inbred mouse strains C57BL/6J and C3H/HeJ.Expand
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Forebrain lesions disrupt development but not maintenance of song in passerine birds.
The magnocellular nucleus of the anterior neostriatum is a forebrain nucleus of passerine birds that accumulates testosterone and makes monosynaptic connections with other telencephalic nuclei thatExpand
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Sexual dimorphism in vocal control areas of the songbird brain.
In canaries and zebra finches, three vocal control areas in the brain are strikingly larger in males than in females. A fourth, area X of the lobus parolfactorius, is well developed in males of bothExpand
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Dosage compensation is less effective in birds than in mammals
Background In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical for species survival. Diverse molecular mechanisms have evolved toExpand
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Distribution and regulation of telencephalic aromatase expression in the zebra finch revealed with a specific antibody
In songbirds, aromatase (estrogen synthase) activity and mRNA are readily detectable in the brain. This neural aromatization presumably provides estrogen to steroid‐sensitive targets via autocrine,Expand
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Strategies and methods for research on sex differences in brain and behavior.
Female and male brains differ. Differences begin early during development due to a combination of genetic and hormonal events and continue throughout the lifespan of an individual. AlthoughExpand
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Reframing sexual differentiation of the brain
In the twentieth century, the dominant model of sexual differentiation stated that genetic sex (XX versus XY) causes differentiation of the gonads, which then secrete gonadal hormones that actExpand
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The organizational–activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues
  • A. Arnold
  • Biology, Medicine
  • Hormones and Behavior
  • 1 May 2009
The 1959 publication of the paper by Phoenix et al. was a major turning point in the study of sexual differentiation of the brain. That study showed that sex differences in behavior, and by extensionExpand
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Chromosomal polymorphism and comparative painting analysis in the zebra finch
The zebra finch (Taeniopygia guttata) is often studied because of its interesting behaviour and neurobiology. Genetic information on this species has been lacking, making analysis of informativeExpand
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