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TYROBP wt Allele

Known as: TYRO Protein Tyrosine Kinase Binding Protein wt Allele, PLO-SL, TYROBP 
Human TYROBP wild-type allele is located in the vicinity of 19q13.1 and is approximately 4 kb in length. This allele, which encodes TYRO protein… 
National Institutes of Health

Related topics

Related topics

7 relations
19q13.1Ligand BindingPOLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHYSignal Transduction

Papers overview

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Highly Cited
2008
Highly Cited
2008
PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon
Type I interferons (IFNs) derived from plasmacytoid dendritic cells (PDCs) are critical for antiviral responses; however, the… 
Highly Cited
2008
Highly Cited
2008
Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells.
We have analyzed leukocyte mono-Ig-like receptor 5 (LMIR5) as an activating receptor among paired LMIRs. Mouse LMIR5 (mLMIR5) is… 
2007
2007
Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection1
Transmembrane signaling adaptor DAP12 has increasingly been recognized for its important role in innate responses. However, its… 
Review
2007
Review
2007
Immunoreceptor-like signaling by beta 2 and beta 3 integrins.
Although adhesion to extracellular structures is one of the most fundamental cell biological processes, the intracellular signals… 
2005
2005
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12
DAP12 is an immunoreceptor tyrosine‐based activation motif‐bearing membrane adapter molecule expressed by different cell types… 
Highly Cited
2004
Highly Cited
2004
IL-4 Confers NK Stimulatory Capacity to Murine Dendritic Cells: A Signaling Pathway Involving KARAP/DAP12-Triggering Receptor Expressed on Myeloid Cell 2 Molecules1
Dendritic cells (DC) regulate NK cell functions, but the signals required for the DC-mediated NK cell activation, i.e., DC… 
2002
2002
Massive inflammatory syndrome and lymphocytic immunodeficiency in KARAP/DAP12‐transgenic mice
KARAP/DAP12 is a broadly distributed transmembrane signaling polypeptide with an immunoreceptor tyrosine‐based activation motif… 
Review
2001
Review
2001
Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49
Once thought to be promiscuous killers, it is now known that natural killer (NK) cells possess an elaborate array of receptors… 
2000
2000
Association of signal-regulatory proteins beta with KARAP/DAP-12.
The signal-regulatory proteins (SIRP) are Ig-like cell surface receptors detected in hematopoietic and non-hematopoietic cells… 
Highly Cited
1999
Highly Cited
1999
Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H
The ability of several Ly49 family members to inhibit natural killer (NK) cell functions through recruitment of SHP‐1 phosphatase… 
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