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TUSC2 wt Allele

Known as: C3orf11, PDAP2, PAP 
Human TUSC2 wild-type allele is located in the vicinity of 3p21.3 and is approximately 3 kb in length. This allele, which encodes tumor suppressor… 
National Institutes of Health

Related topics

Related topics

8 relations
3p21.3Cell Proliferation Regulatory ProcessHomo sapiensInhibition of Cancer Cell Growth

Broader (1)

TUSC2 gene

Papers overview

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2016
2016
A phase I trial of intravenous therapy with tumor suppressor FUS1-nanoparticles for recurrent/metastatic lung cancer.
e19065 Background: The tumor suppressor gene FUS1 is frequently inactivated early in lung cancer development. FUS1 mediates… 
2015
2015
Cellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice
Mechanism of radiosensitivity of normal tissues, a key factor in determining the toxic side effects of cancer radiotherapy, is… 
2014
2014
Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo
PurposeLKB1 and FUS1 are two kinds of new tumor suppressor genes as well as early-stage genes in lung cancer. Recent studies… 
2014
2014
Cationic liposome mediated delivery of FUS1 and hIL-12 coexpression plasmid demonstrates enhanced activity against human lung cancer.
FUS1 is one of the most important tumor suppressor genes in lung cancer, as well as an important immunomodulatory molecule… 
2013
2013
A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1
FUS1/TUSC2 is a mitochondrial tumor suppressor with activity to regulate cellular oxidative stress by maintaining balanced ROS… 
2011
2011
Regulation of tumor suppressor gene FUS1 expression by the untranslated regions of mRNA in human lung cancer cells.
2008
2008
Small-Interference RNA Gene Knockdown of Pancreatitis-Associated Proteins in Rat Acute Pancreatitis
Objectives: Pancreatitis-associated proteins (PAPs) are induced in acute pancreatitis and antisense-mediated gene knockdown of… 
Highly Cited
2007
Highly Cited
2007
Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent…
FUS1 is a novel tumor suppressor gene identified in human chromosome 3p21.3 region. Loss of expression and deficiency of… 
1990
1990
CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast.
Mutations in either the CDC36 or CDC39 gene cause yeast cells to arrest in G1 of the cell cycle at the same point as treatment… 
1986
1986
Comparison of Peroxidase‐Antiperoxidase and Avidin‐Biotin Complex Methods for the Detection of Papillomavirus in Histological Sections of the Cervix Uteri
&NA; Summary A study was undertaken to determine the relative sensitivities of the peroxidase‐antiperoxidase (PAP) and avidin… 
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