TSC1 protein, human

Known as: hamartin protein, human, Hamartin, tuberous sclerosis 1 protein, human 
Hamartin (1164 aa, ~130 kDa) is encoded by the human TSC1 gene. This protein is involved in the negative regulation of signaling.
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have… (More)
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Review
2006
Review
2006
BCAAs stimulate protein synthesis in in vitro preparations of skeletal muscle. Likewise, the stimulation of protein synthesis in… (More)
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Highly Cited
2006
Highly Cited
2006
The mammalian target of rapamycin (mTOR), a critical modulator of cell growth, acts to integrate signals from hormones, nutrients… (More)
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Review
2005
Review
2005
The most exciting advances in the tuberous sclerosis complex (TSC) field occurred in 1993 and 1997 with the cloning of the TSC2… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Tuberous Sclerosis Complex (TSC) is a genetic disorder that occurs through the loss of heterozygosity of either TSC1… (More)
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Highly Cited
2002
Highly Cited
2002
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that occurs upon mutation of either the TSC1 or TSC2… (More)
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Highly Cited
2000
Highly Cited
2000
Loss of the tumour-suppressor gene TSC1 is responsible for hamartoma development in tuberous sclerosis complex (TSC), which… (More)
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Highly Cited
2000
Highly Cited
2000
We report here that overexpression of the tuberous sclerosis-1 (TSC1) gene product hamartin results in the inhibition of growth… (More)
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Highly Cited
1998
Highly Cited
1998
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by a mutation in either the TSC1 or TSC2 tumour suppressor gene… (More)
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Highly Cited
1998
Highly Cited
1998
Tuberous sclerosis is an inherited syndrome associated with mutations in two tumor suppressor genes: TSC1 and TSC2. Tuberin, the… (More)
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