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TRPV Cation Channels

Known as: Receptors, Capsaicin, Cation Channels, TRPV, vanilloid receptor 
A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They… 
National Institutes of Health

Related topics

Related topics

16 relations
Ankyrin RepeatIn BloodProcess of secretionTRPV1 gene

Narrower (6)

OCR-2 protein, C elegansTRPV1 receptorTRPV2 protein, humanTRPV6 channel

Papers overview

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Highly Cited
2009
Highly Cited
2009
Inhibition of human recombinant T‐type calcium channels by the endocannabinoid N‐arachidonoyl dopamine
Background and purpose:  N‐arachidonoyl dopamine (NADA) has complex effects on nociception mediated via cannabinoid CB1 receptors… 
Review
2005
Review
2005
The vanilloid receptor and hypertension
AbstractMammalian transient receptor potential (TRP) channels consist of six related protein sub-families that are involved in a… 
Review
2004
Review
2004
Recent developments in transient receptor potential vanilloid receptor 1 agonist-based therapies
Capsaicin and other naturally occurring pungent molecules have been used for centuries as topical analgesics and rubefactants to… 
Highly Cited
2004
Highly Cited
2004
Trypsin mediates nociception via the proteinase-activated receptor 2: a potentially novel role in pancreatic pain.
BACKGROUND & AIMS The pathogenesis of pain in pancreatitis remains poorly understood. We hypothesized that trypsin, a key… 
Highly Cited
2003
Highly Cited
2003
Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM.
It is well established that the vanilloid receptor, VR1, is an important peripheral mediator of nociception. VR1 receptors are… 
Highly Cited
2003
Highly Cited
2003
Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti.
Capsaicin, the vanilloid that selectively activates vanilloid receptors (VRs) on sensory neurons for noxious perception, has been… 
Highly Cited
2002
Highly Cited
2002
Vanilloid Receptors Presynaptically Modulate Cranial Visceral Afferent Synaptic Transmission in Nucleus Tractus Solitarius
Although the central terminals of cranial visceral afferents express vanilloid receptor 1 (VR1), little is known about their… 
Highly Cited
2002
Highly Cited
2002
Cloning and functional characterization of the guinea pig vanilloid receptor 1
Highly Cited
2002
Highly Cited
2002
Vanilloid-Sensitive Afferents Activate Neurons with Prominent A-Type Potassium Currents in Nucleus Tractus Solitarius
Cranial visceral afferents innervate second-order nucleus tractus solitarius (NTS) neurons via myelinated (A-type) and… 
Highly Cited
2000
Highly Cited
2000
Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology
The vanilloid receptor (VR1) is a ligand‐gated ion channel, which plays an important role in nociceptive processing. Therefore, a… 
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