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TRK 820

Known as: TRK-820 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

MorphinansSpiro Compounds

Narrower (2)

nalfurafinenalfurafine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Topical nalfurafine exhibits anti-inflammatory and anti-pruritic effects in a murine model of AD.
2012
2012
Opioid Kappa Receptor Selective Agonist TRK-820 (Nalfurafine Hydrochloride)
pharmacology history of and the frontiers of pharmacology a new world in the of drugs. New technologies and continuing progress… 
Review
2011
Review
2011
Opioids in preclinical and clinical trials.
Since 1952, when Gates determined the stereo structure of morphine, numerous groups have focused on discovering a nonnarcotic… 
2008
2008
[Effect of TRK-820, a selective kappa opioid receptor agonist, on scratching behavior in an animal model of atopic dermatitis].
In atopic dermatitis patients, pruritus is a severe symptom that is difficult to treat. It is previously reported that TRK-820, a… 
2006
2006
Generalization of NMDA-receptor antagonists to the discriminative stimulus effects of kappa-opioid receptor agonists U-50,488H, but not TRK-820 in rats.
Generalizations of NMDA-receptor antagonists to the discriminative stimulus effects of kappa-opioid receptor agonists in rats… 
2005
2005
Spontaneous scratching behavior in MRL/lpr mice, a possible model for pruritus in autoimmune diseases, and antipruritic activity of a novel kappa-opioid receptor agonist nalfurafine hydrochloride.
2004
2004
Syntheses of potential metabolites of a potent kappa-opioid receptor agonist, TRK-820.
Chemical syntheses of three kinds of potential metabolites of TRK-820, a potent kappa-opioid receptor agonist, were described… 
Highly Cited
2002
Highly Cited
2002
Functional Effects of Systemically Administered Agonists and Antagonists of , , and Opioid Receptor Subtypes on Body Temperature in Mice
We have investigated the roles of peripheral and central , , and opioid receptors and their subtypes in opioid-induced… 
2002
2002
TRK-820, a selective κ-opioid agonist, produces potent antinociception in cynomolgus monkeys
2000
2000
The novel kappa-opioid receptor agonist TRK-820 has no affect on the development of antinociceptive tolerance to morphine in mice.
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