nalfurafine hydrochloride
National Institutes of Health
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BackgroundPatients with primary biliary cholangitis (PBC) frequently suffer from pruritus, which can severely impair their health…
Pruritus is one of the complications of chronic liver disease, and it is important to investigate the predictors.
Patients with chronic liver disease sometimes develop cholestasis, which induces severe whole‐body pruritus that may disrupt…
Background and aim Among various symptoms accompanied with chronic liver disease, pruritus affects the quality of life of…
Uremic pruritus has a great negative influence on quality of life in hemodialysis (HD) patients and, importantly, negatively…
Nalfurafine (nalfurafine hydrochloride, TRK-820, Remitch®) was launched as an anti-pruritic for uremic pruritus in hemodialysis…
Chronic pruritus is frequently refractory to currently available treatments. Studies suggest that pruritus may arise from an…
Background: Our previous placebo-controlled, prospective, double-blind study demonstrated that a new opioid ĸ-receptor agonist…
Introduction: Severe pruritus associated with end-stage renal disease is a particularly troublesome complication, because no…