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TRH gene

Known as: TRH, prothyroliberin, Thyrotropin-Releasing Hormone Gene 
This gene plays a regulatory role in the biosynthesis of thyroid stimulating hormone.
National Institutes of Health

Related topics

Related topics

7 relations
Hypothalamic hypothyroidismIntercellular Communication ProcessProtein SecretionSynaptic Transmission

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TRH wt Allele

Papers overview

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Highly Cited
2002
Highly Cited
2002
Homo- and Hetero-oligomerization of Thyrotropin-releasing Hormone (TRH) Receptor Subtypes
G-protein-coupled receptors (GPCRs) are regulated by a complex network of mechanisms such as oligomerization and internalization… 
1993
1993
The effect of dietary protein on thyrotropin-releasing hormone and thyrotropin gene expression
Review
1992
Review
1992
Evidence for hypothalamo-growth hormone dysfunction in panic disorder: profile of growth hormone (GH) responses to clonidine, yohimbine, caffeine, glucose, GRF and TRH in panic disorder patients…
Given the abrupt and time-limited nature of daytime-awake and nocturnal-sleep panic attacks, several chemical and neuroendocrine… 
1988
1988
Vasoconstrictor effects in spinal cord of the substance P antagonist [D-ARG1, D-TRP7,9, LEU11] substance P (spantide) and somatostatin and interaction with thyrotropin releasing hormone
Highly Cited
1987
Highly Cited
1987
Identification and characterization of thyrotropin-releasing hormone precursor peptides in rat brain.
The sequence of rat hypothalamic pro-TRH, deduced by sequencing of cDNA, contains five copies of the TRH progenitor sequence Gln… 
Highly Cited
1986
Highly Cited
1986
Delineation of a Particulate Thyrotropin‐Releasing Hormone‐Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase
Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N… 
Highly Cited
1983
Highly Cited
1983
Pituitary adenomas in acromegalic patients: an immunohistochemical and endocrinological study with special reference to prolactin-secreting adenoma.
To establish a functional classification of purification of pituitary adenomas in acromegalic patients, we used immunoperoxidase… 
Highly Cited
1982
Highly Cited
1982
Effect of chronic immunoneutralization of thyrotropin-releasing hormone on the hypothalamic-pituitary-thyroid axis, prolactin, and reproductive function in the ewe.
The physiological role of TRH was studied by chronic neutralization of its action by actively immunizing six adult ewes against… 
Highly Cited
1981
Highly Cited
1981
The 7315a pituitary tumor is refractory to dopaminergic inhibition of prolactin release but contains dopamine receptors.
The PRL-secreting pituitary tumor 7315a was grown in female rats, tested for its biological responsiveness, and monitored for the… 
1979
1979
Metabolic clearance of thyrotropin-releasing hormone in the rat in hypothyroid and hyperthyroid states: comparison with serum degradation in vitro.
The effect of thyroid status on the metabolic clearance of TRH was studied in the rat. TRH (2 μg) was administered iv to… 
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