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TRAF2 gene

Known as: TNF RECEPTOR-ASSOCIATED FACTOR 2, TNF receptor associated factor 2, TNF Receptor-Associated Factor 2 Gene 
This gene is involved in signal transduction and inhibition of apoptosis.
National Institutes of Health

Related topics

Related topics

7 relations
CD40 LigandCD40LG geneNegative Regulation of ApoptosisSignal Transduction

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TRAF2 wt Allele

Papers overview

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2015
2015
TRAF 2 regulates TNF and NF-κB signalling to suppress apoptosis and skin 1 inflammation independently of Sphingosine kinase-1 2 3
2012
2012
The skeletal muscle-metabolism axis in prostate-cancer therapy.
n engl j med 367;23 nejm.org december 6, 2012 2257 and 5 of 11 patients with IgM MGUS (45%), as defined by consensus criteria,1… 
2012
2012
TRAF2 Governs the T Cell Alloimmune Response: 1366
2009
2009
TRAF 2 and TRAF 3 independently mediate Ig class switching driven by CD 40 Haifa
The isotype switch defect in CD40 mice is corrected by wild-type (WT) CD40 transgene, but not by a mutant CD40 transgene that… 
2007
2007
The Relationship between NF-κBp65 and TRAF2 Expression and Apoptosis in Oral Lichen Planus
2007
2007
Biological Sequelae of TRAF2 Downregulation in Waldenstrom Macroglobulinemia Cells.
Background. Several TNF family members (CD40L and BAFF/BLYS) have been implicated in Waldenstrom’s Macroglobulinemia (WM) cell… 
2003
2003
Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling
2002
2002
TNF RECEPTOR ASSOCIATED FACTORS 2 AND 6 REGULATE RANKL AND TNF-INDUCED OSTEOCLASTOGENESIS
  • 2002
  • Corpus ID: 36725970
Introduction and Significance: Osteolysis, erosive arthritis, bone metastasis and other bone pathologies are a constant clinical… 
2001
2001
Expression of ring ® nger-deleted TRAF 2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p 38 , TNF a and suppression of NFk B activities
Mechanisms underlying radiation and chemotherapy resistance, the hallmark of human melanoma, are not well understood. Here we… 
1999
1999
CD40-mediated activation of Ig-Cgamma1- and Ig-cepsilon germ-line promoters involves multiple TRAF family proteins.
CD40 plays a critical role in immunoglobulin (Ig) class switching in B cells, but the molecular events involved remain poorly…