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TNKS gene

Known as: Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase Gene, TANKYRASE 1, TRF1-interacting ankyrin-related ADP-ribose polymerase 1 
This gene is involved in telomere maintenance and protein-protein interaction mediation.
National Institutes of Health

Related topics

Related topics

4 relations
TNKS wt AlleleTankyraseTankyrasesTelomere Maintenance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer
Activation of Wnt/β-catenin signaling is essential for colorectal carcinogenesis. Tankyrase, a member of the poly(ADP-ribose… 
2015
2015
Tankyrase-mediated β-catenin activity regulates vasopressin-induced AQP2 expression in kidney collecting duct mpkCCDc14 cells.
Aquaporin-2 (AQP2) mediates arginine vasopressin (AVP)-induced water reabsorption in the kidney collecting duct. AVP regulates… 
2015
2015
Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics.
2014
2014
The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin.
2014
2014
Sighting of tankyrase inhibitors by structure- and ligand-based screening and in vitro approach.
Tankyrase 1 and 2 (TNKS) are promising and attractive therapeutic targets in anticancer drug development. Herein, we report the… 
Review
2012
Review
2012
Complex roles of members of the ADP-ribosyl transferase super family in immune defences: looking beyond PARP1.
2010
2010
Characterization of a Plant-Specific Gene Induced by Endoplasmic Reticulum Stress in Arabidopsis thaliana
We have conducted transcriptome analysis and have identified a number of genes that are upregulated by treatment with the… 
2003
2003
The formin‐binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance
2002
2002
[Calculating emissions of exhaust particulate matter from motor vehicles with PART5 model].
PART5, a vehicle particulate emission factor model developed by USEPA, was modified and then used to obtain the emission factors… 
Highly Cited
2001
Highly Cited
2001
Identification of a Novel Human Tankyrase through Its Interaction with the Adaptor Protein Grb14*
Tankyrase is an ankyrin repeat-containing poly(ADP-ribose) polymerase originally isolated as a binding partner for the telomeric… 
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