Telomere Maintenance

Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Orthologs of the yeast telomere protein Stn1 are present in plants, but other components of the Cdc13/Stn1/Ten1 (CST) complex… (More)
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Review
2008
Review
2008
The genomes of prokaryotes and eukaryotic organelles are usually circular as are most plasmids and viral genomes. In contrast… (More)
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Highly Cited
2007
Highly Cited
2007
Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has opened the way to their clinical use… (More)
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Highly Cited
2004
Highly Cited
2004
The five RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) are required in mammalian cells for normal levels of genetic… (More)
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Review
2002
Review
2002
Maintenance of telomeres — specialized complexes that protect the ends of chromosomes — is undertaken by the enzyme complex… (More)
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Highly Cited
1999
Highly Cited
1999
Many Saccharomyces telomeres bear one or more copies of the repetitive Y' element followed by approximately 350 bp of telomerase… (More)
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Highly Cited
1998
Highly Cited
1998
The immortalization of human cells is a critical step during tumorigenesis. In vitro, normal human somatic cells must overcome… (More)
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Highly Cited
1998
Highly Cited
1998
Telomeres are functionally distinct from ends generated by chromosome breakage, in that telomeres, unlike double-strand breaks… (More)
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Highly Cited
1993
Highly Cited
1993
Yeast cells lacking a functional EST1 gene show progressive shortening of the terminal G1-3T telomeric repeats and a parallel… (More)
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Highly Cited
1989
Highly Cited
1989
I have identified an activity in crude HeLa cell extracts that satisfies the requirements for a human telomere terminal… (More)
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