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Telomere Maintenance

Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The finding that transcription occurs at chromosome ends has opened new fields of study on the roles of telomeric transcripts in… Expand
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Review
2008
Review
2008
The genomes of prokaryotes and eukaryotic organelles are usually circular as are most plasmids and viral genomes. In contrast… Expand
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Highly Cited
2007
Highly Cited
2007
Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has opened the way to their clinical use… Expand
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Review
2002
Review
2002
Maintenance of telomeres — specialized complexes that protect the ends of chromosomes — is undertaken by the enzyme complex… Expand
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Highly Cited
1999
Highly Cited
1999
Mammalian telomeres contain a duplex array of telomeric repeats bound to the telomeric repeat-binding factors TRF1 and TRF2… Expand
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Highly Cited
1998
Highly Cited
1998
The immortalization of human cells is a critical step during tumorigenesis. In vitro, normal human somatic cells must overcome… Expand
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Highly Cited
1996
Highly Cited
1996
The CDC13 gene has previously been implicated in the maintenance of telomere integrity in Saccharomyces cerevisiae. With the use… Expand
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Highly Cited
1993
Highly Cited
1993
Yeast cells lacking a functional EST1 gene show progressive shortening of the terminal G1-3T telomeric repeats and a parallel… Expand
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Review
1991
Review
1991
The DNA of telomeres—the terminal DNA-protein complexes of chromosomes—differs notably from other DNA sequences in both structure… Expand
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Highly Cited
1989
Highly Cited
1989
I have identified an activity in crude HeLa cell extracts that satisfies the requirements for a human telomere terminal… Expand
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