Tankyrase

Known as: TNKS, Telomeric Poly (ADP-Ribose) Polymerase, Telomeric Poly-(ADP-Ribose)-Polymerase 
Tankyrase-1 (1327 aa, ~142 kDa) is encoded by the human TNKS gene. This protein plays a role in poly-ADP-ribosylation of protein substrates.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Aggregation of misfolded proteins and the associated loss of neurons are considered a hallmark of numerous neurodegenerative… (More)
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Review
2013
Review
2013
Diabetes is now regarded as an epidemic, with the population of patients expected to rise to 380 million by 2025. Tragically… (More)
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2013
2013
Recently a novel inhibitor of Wnt signaling was discovered. The compound, WIKI4, was found to act through tankyrase inhibition… (More)
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Review
2012
Review
2012
The poly(ADP-ribose) polymerase (PARP) protein superfamily has wide-ranging roles in cellular processes such as DNA repair and… (More)
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2012
2012
During prometaphase, dense microtubule nucleation sites at centrosomes form robust spindles that align chromosomes promptly… (More)
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2010
2010
Garcinol, derived from Garcinia indica and other related species, has been found to modulate several cell signalling pathways… (More)
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2007
2007
BACKGROUND The enzyme tankyrase-1 (TNKS-1), a member of the growing family of poly(ADP-ribose) polymerases (PARPs), was… (More)
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Highly Cited
2005
Highly Cited
2005
Poly(ADP-ribose) (PAR) is a large, negatively charged post-translational modification that is produced by polymerization of NAD… (More)
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Highly Cited
2002
Highly Cited
2002
The poly(ADP-ribose) polymerase (PARP) tankyrase-1 contains an ankyrin-repeat domain that binds to various partners, including… (More)
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Highly Cited
2002
Highly Cited
2002
Boswellic acids are the effective components of gum resin of Boswellia serrata, which has anti-inflammatory properties. Recent… (More)
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