Tankyrases

Known as: TRF-1 Interacting, Ankyrin-Related, ADP-Ribose Polymerases, Tankyrases [Chemical/Ingredient] 
A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and have poly(ADP-ribose) polymerase activity.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
0246820032018

Papers overview

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2013
2013
Tankyrases 1 and 2 (TNKS1/2) are promising pharmacological biotargets with possible applications for the development of novel… (More)
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2012
2012
Tankyrases are poly(ADP-ribose) polymerases that have many cellular functions. They play pharmaceutically important roles, at… (More)
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2012
2012
Constitutive Wnt signalling is characterized by excessive levels of β-catenin protein and is a frequent occurrence in cancer. APC… (More)
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2012
2012
Tankyrases (TNKS1 and TNKS2) are key regulators of cellular processes such as telomere pathway and Wnt signaling. IWRs… (More)
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Highly Cited
2011
Highly Cited
2011
The poly(ADP-ribose)polymerases Tankyrase 1/2 (TNKS/TNKS2) catalyze the covalent linkage of ADP-ribose polymer chains onto target… (More)
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2010
2010
We report two crystal structures of the PARP domain of human tankyrase-2 (TNKS2). Tankyrases are involved in fundamental cellular… (More)
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2008
2008
Tankyrases are proteins with poly(ADP-ribose) polymerase activity. Human tankyrases post-translationally modify multiple proteins… (More)
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2008
2008
Tankyrases are recently discovered proteins implicated in many important functions in the cell including telomere homeostasis and… (More)
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2004
2004
Tankyrases are novel poly(ADP-ribose) polymerases that have SAM and ankyrin protein-interaction domains. They are found at… (More)
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2003
2003
Tankyrases 1 and 2 are two highly related poly(ADP-ribose) polymerases that interact with a variety of cytoplasmic and nuclear… (More)
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