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Tankyrases

Known as: TRF-1 Interacting, Ankyrin-Related, ADP-Ribose Polymerases, Tankyrases [Chemical/Ingredient] 
A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and have poly(ADP-ribose) polymerase activity.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
As the key effector in the Hippo pathway, YAP was identified as an oncoprotein whose expression is elevated in various human… Expand
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Review
2014
Review
2014
Several cellular signaling pathways are regulated by ADP-ribosylation, a posttranslational modification catalyzed by members of… Expand
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Review
2013
Review
2013
Tankyrase 1 and tankyrase 2 are poly(ADP-ribosyl)ases that are distinguishable from other members of the enzyme family by the… Expand
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Highly Cited
2013
Highly Cited
2013
Tankyrases 1 and 2 (TNKS1/2) are promising pharmacological biotargets with possible applications for the development of novel… Expand
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Highly Cited
2012
Highly Cited
2012
Constitutive Wnt signalling is characterized by excessive levels of β-catenin protein and is a frequent occurrence in cancer. APC… Expand
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Highly Cited
2012
Highly Cited
2012
BackgroundNew pharmacologic targets are urgently needed to treat or prevent lung cancer, the most common cause of cancer death… Expand
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Highly Cited
2012
Highly Cited
2012
Tankyrases are poly(ADP-ribose) polymerases that have many cellular functions. They play pharmaceutically important roles, at… Expand
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Highly Cited
2011
Highly Cited
2011
(Cell 147, 1340–1354; December 9, 2011) In Table S4 of the above article, the accessory information within the last five columns… Expand
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Highly Cited
2011
Highly Cited
2011
The poly(ADP-ribose)polymerases Tankyrase 1/2 (TNKS/TNKS2) catalyze the covalent linkage of ADP-ribose polymer chains onto target… Expand
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Highly Cited
2008
Highly Cited
2008
Tankyrases are proteins with poly(ADP-ribose) polymerase activity. Human tankyrases post-translationally modify multiple proteins… Expand
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