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TNKS wt Allele

Known as: TNKS1, TINF1, TIN1 
Human TNKS wild-type allele is located in the vicinity of 8p23.1 and is approximately 226 kb in length. This allele, which encodes tankyrase-1… Expand
National Institutes of Health

Papers overview

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2016
2016
  • Bo Li, R. Qiao, +4 authors Z. Rao
  • Acta crystallographica. Section F, Structural…
  • 2016
  • Corpus ID: 4522640
Telomere repeat factor 1 (TRF1) is a subunit of shelterin (also known as the telosome) and plays a critical role in inhibiting… Expand
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Highly Cited
2015
Highly Cited
2015
Deregulated WNT/β-catenin signaling contributes to the development of a subgroup of hepatocellular carcinoma (HCC), the second… Expand
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2014
2014
Tankyrases (TNKS) belong to the poly(ADP-ribose)polymerase (PARP) protein super family and play a vital role in the Wnt/β-catenin… Expand
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Highly Cited
2013
Highly Cited
2013
BackgroundNeuroblastoma (NB) is the most common extracranial solid tumor in childhood. The present treatment including surgery… Expand
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Highly Cited
2013
Highly Cited
2013
Telomeres are involved in maintaining genomic stability. Previous studies have linked both telomere length (TL) and telomere… Expand
2013
2013
Tankyrase (TNKS) is a poly-ADP-ribosylating protein (PARP) whose activity suppresses cellular axin protein levels and elevates… Expand
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Highly Cited
2012
Highly Cited
2012
Inhibitors of poly-ADP-ribose polymerase (PARP) family proteins are currently in clinical trials as cancer therapeutics, yet the… Expand
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Highly Cited
2012
Highly Cited
2012
BackgroundNew pharmacologic targets are urgently needed to treat or prevent lung cancer, the most common cause of cancer death… Expand
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Highly Cited
2010
Highly Cited
2010
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new… Expand
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Highly Cited
2009
Highly Cited
2009
This study was conducted to comprehensively evaluate the associations between polymorphisms in telomere maintenance genes (TERT… Expand
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