Skip to search formSkip to main contentSkip to account menu

TGFBR1 gene

Known as: ALK-5, ACTIVIN RECEPTOR-LIKE KINASE 5, TGFBR1 
This gene is involved in transcriptional regulation and cell cycle progression regulation.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Cycle ProgressionLigand BindingPhosphorylationReceptor Signaling

Narrower (1)

TGFBR1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Long noncoding RNA GAS5 attenuates cardiac fibroblast proliferation in atrial fibrillation via repressing ALK5.
OBJECTIVE Recently, long noncoding RNAs (lncRNAs) have caught more attention for their role in the progression of many diseases… 
Highly Cited
2010
Highly Cited
2010
Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro.
2009
2009
Stage-specific expression of bone morphogenetic protein type I and type II receptor genes: Effects of follicle-stimulating hormone on ovine antral follicles.
2009
2009
Differential responses to oxidative stress and calcium influx on expression of the transforming growth factor‐β family in myoblasts and myotubes
Changes in gene expression of TGF‐β family members and their receptors in response to treatment with H2O2 and a calcium ionophore… 
2009
2009
The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer
A polymorphic 9-bp deletion in exon 1 of TGFBR1 (TGFBR1*6A) has been identified as a low-penetrance cancer susceptibility allele… 
2009
2009
Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles and 1,3,5-trisubstituted pyrazoles as inhibitors of transforming growth factor beta type 1 receptor (ALK5).
2006
2006
A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy.
OBJECTIVE Transforming growth factor beta (TGFbeta)-activated kinase 1 (TAK1) is a MAP kinase kinase kinase involved in numerous… 
1998
1998
A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice.
TGF beta family members are implicated in cardiac organogenesis, growth control, and positional information, including the… 
1995
1995
Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively.
Transforming growth factor-{Beta} (TGF-{beta}) is a multifunctional cytokine, known to modulate several tissue development and… 
1995
1995
Molecular characterization of a type I serine-threonine kinase receptor for TGF-beta and activin in the rat pituitary tumor cell line GH3.
GH3 pituitary tumor cells have surface receptors for transforming growth factors-beta (TGF-beta s) and activins/inhibins. GH3… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)