TGFBR1 gene

Known as: ALK-5, ACTIVIN RECEPTOR-LIKE KINASE 5, TGFBR1 
This gene is involved in transcriptional regulation and cell cycle progression regulation.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
VE-cadherin is an endothelial-specific transmembrane protein concentrated at cell-to-cell adherens junctions. Besides promoting… (More)
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Highly Cited
2006
Highly Cited
2006
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder characterized by manifestations in the cardiovascular… (More)
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2006
2006
The recent identification of TGFBR2 mutations in Marfan syndrome II (MFSII) [Mizuguchi et al. (2004); Nat Genet 36:855-860] and… (More)
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Highly Cited
2005
Highly Cited
2005
Pulmonary fibrosis is characterized by chronic scar formation and deposition of extracellular matrix, resulting in impaired lung… (More)
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Highly Cited
2005
Highly Cited
2005
Transforming growth factor (TGF)-beta signaling facilitates tumor growth and metastasis in advanced cancer. Use of inhibitors of… (More)
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Highly Cited
2002
Highly Cited
2002
The generation of mice lacking specific components of the transforming growth factor-beta (TGF-beta) signal tranduction pathway… (More)
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Highly Cited
2002
Highly Cited
2002
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… (More)
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Highly Cited
1998
Highly Cited
1998
Transforming growth factor beta (TGF-beta) is an extracellular ligand that binds to a heterodimeric receptor, initiating signals… (More)
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Highly Cited
1995
Highly Cited
1995
Bone morphogenetic proteins (BMPs) are multifunctional proteins structurally related to transforming growth factor-beta (TGF beta… (More)
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Highly Cited
1994
Highly Cited
1994
Bone morphogenetic proteins (BMPs) are multifunctional proteins, structurally related to transforming growth factor-beta (TGF… (More)
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