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TGFBR1 wt Allele

Known as: ACVRLK4, Transforming Growth Factor, Beta Receptor I (Activin A Receptor Type II-Like Kinase, 53kDa) wt Allele, TGFBR1 
Human TGFBR1 wild-type allele is located within 9q22 and is approximately 45 kb in length. This allele, which encodes TGF-beta receptor type-1… Expand
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND & AIMS: Early-onset gastric cancer, which develops in patients younger than most gastric cancers, is usually detected… Expand
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2016
2016
Background—The natural history of aortic diseases in patients with TGFBR1 or TGFBR2 mutations reported by different investigators… Expand
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Highly Cited
2012
Highly Cited
2012
Patients with mutations in either TGF-β receptor type I (TGFBR1) or TGF-β receptor type II (TGFBR2), such as those with Loeys… Expand
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Highly Cited
2009
Highly Cited
2009
Background: Mutations in the transforming growth factor β receptor type I and II genes (TGFBR1 and TGFBR2) cause Loeys–Dietz… Expand
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2009
2009
BackgroundTGFBR1*6A is a common hypomorphic variant of transforming growth factor β receptor 1 (TGFBR1). TGFBR1*6A is associated… Expand
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2008
2008
TGFBR1*6A is a common hypomorphic variant of the type 1 transforming growth factor beta receptor (TGFBR1), which has been… Expand
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Highly Cited
2006
Highly Cited
2006
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder characterized by manifestations in the cardiovascular… Expand
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2004
2004
TGF-beta signaling is frequently perturbed in many human cancers, including renal cell carcinomas (RCCs) and transitional cell… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE TGFBR1*6A is a hypomorphic polymorphic allele of the type I transforming growth factor beta receptor (TGFBR1). TGFBR1*6A… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Some animal studies suggest that transforming growth factor-beta (TGF-beta) protects vessels from atherosclerosis by… Expand
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